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CPT1C 抗体 (AA 121-170) (Biotin)

This anti-CPT1C antibody is a 兔 多克隆 antibody detecting CPT1C in WB, ELISA, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN1391149
发货至: 中国

Quick Overview for CPT1C 抗体 (AA 121-170) (Biotin) (ABIN1391149)

抗原

See all CPT1C 抗体
CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))

适用

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宿主

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克隆类型

  • 52
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多克隆

标记

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This CPT1C antibody is conjugated to Biotin

应用范围

  • 38
  • 27
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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 7
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    AA 121-170

    预测反应

    Human,Mouse,Rat,Dog,Cow,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Cpt1c

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))

    别名

    Cpt1c

    背景

    Synonyms: CPT1-C, Carnitine acyltransferase like protein 1, Carnitine acyltransferase like protein1, Carnitine O palmitoyltransferase I, brain isoform, Carnitine palmitoyltransferase 1, brain, Carnitine palmitoyltransferase 1C, Carnitine palmitoyltransferase I related C, Carnitine palmitoyltransferase1C, CAT L1, CATL 1, CATL1, CPT 1 like pseudogene, Cpt 1c, CPT 1P, CPT I C, Cpt1 c, CPT1 like pseudogene, CPT1P , CPTIC.CPT1C_HUMAN

    Background: The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine.

    基因ID

    126129

    途径

    AMPK Signaling, Monocarboxylic Acid Catabolic Process
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