SNAP29 抗体 (AA 181-258) (AbBy Fluor® 350)
Quick Overview for SNAP29 抗体 (AA 181-258) (AbBy Fluor® 350) (ABIN1390827)
抗原
See all SNAP29 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 181-258
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human SNAP29
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- SNAP29 (Synaptosomal-Associated Protein, 29kDa (SNAP29))
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别名
- SNAP29
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背景
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Synonyms: SNAP 29, SNAP-29, SNAP29, SNP29_HUMAN, Soluble 29 kDa NSF attachment protein, Synaptosomal associated protein 29, Synaptosomal associated protein 29 kDa, Synaptosomal-associated protein 29, Vesicle membrane fusion protein SNAP 29, Vesicle membrane fusion protein SNAP29, Vesicle-membrane fusion protein SNAP-29, CEDNIK, FLJ21051.
Background: SNAP 29 is a 258 amino acid protein that localizes to the membrane and the cytoplasm, as well as to the cell junction, and contains one t-SNARE coiled-coil homology domain. Expressed in liver, heart, brain, kidney, placenta, lung, spleen, pancreas and skeletal muscle, SNAP 29 binds tightly to Syntaxins and, via this binding, is involved in membrane trafficking events. Defects in the gene encoding SNAP 29 are the cause of CEDNIK syndrome, a neurocutaneous syndrome that is associated with cerebral dysgenesis, neuropathy, ichthyosis and palmoplantar keratoderma. The gene encoding SNAP 29 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
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基因ID
- 9342
抗原
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