MCM4 抗体 (AA 761-863) (Biotin)
Quick Overview for MCM4 抗体 (AA 761-863) (Biotin) (ABIN1390441)
抗原
See all MCM4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 761-863
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预测反应
- Human,Mouse,Rat,Dog,Cow,Pig,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human MCM4
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亚型
- IgG
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anti-Minichromosome Maintenance Deficient 4 (MCM4) (AA 1-863) antibody
MCM4 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) (AA 1-863) antibodyMCM4 适用: 人 WB, IHC (p), IF 宿主: 小鼠 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) (AA 2-141) antibodyMCM4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) antibodyMCM4 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) (AA 637-665) antibodyMCM4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) (AA 267-366) antibodyMCM4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) (C-Term) antibodyMCM4 适用: 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 犬, 斑马鱼, Pig, 非洲爪蟾, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) (AA 97-146) antibodyMCM4 适用: 人, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) (AA 411-460) antibodyMCM4 适用: 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 犬, 马, 斑马鱼, 猴, Pig, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) (AA 80-129) antibodyMCM4 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 猴, Pig, 非洲爪蟾, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- MCM4 (Minichromosome Maintenance Deficient 4 (MCM4))
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别名
- MCM4/CDC21
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背景
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Synonyms: CDC21, CDC21 homolog, CDC54, DNA replication licensing factor MCM 4, DNA replication licensing factor MCM4, hCdc 21, hCdc21, Homolog of S. pombe cell devision cycle 21, KIAA4003, mcdc21, MCM 4, MCM 4 minichromosome maintenance deficient 4, MCM4, MCM4 minichromosome maintenance deficient 4, MCM4 minichromosome maintenance deficient 4, mitotin S. cerevisiae, MCM4_HUMAN, Mcmd4, MGC33310, Minichromosome Maintenance 4, Minichromosome maintenance complex component 4, Minichromosome maintenance deficient S. cerevisiae 4, Minichromosome maintenance deficient 4, Minichromosome maintenance deficient 4 homolog S. cerevisiae, Minichromosome maintenance, S. cerevisiae, homolog of, 4, mKIAA4003, P1 CDC21, P1-CDC21, P1CDC21, 19G antibody AI325074, AU045576, CDC 21, CDC 54.
Background: The mini-chromosome maintenance (MCM) family of proteins, including MCM2, MCM3, MCM4 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle. Expression of MCM proteins increases during cell growth, peaking at G1 to S phase. The MCM proteins each contain an ATP-binding motif, which is predicted to mediate ATP-dependent opening of double-stranded DNA. MCM proteins are regulated by E2F transcription factors, which induce MCM expression, and by protein kinases, which interact with MCM proteins to maintain the postreplicative state of the cell. MCM2/MCM4 complexes function as substrates for Cdc2/cyclin B in vitro. Cleavage of MCM3, which can be prevented by caspase inhibitors, results in the inactivation of the MCM complex (composed of at least MCM proteins 2-6) during apoptosis.
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途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
抗原
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