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HAS2 抗体 (AbBy Fluor® 555)

This anti-HAS2 antibody is a 兔 多克隆 antibody detecting HAS2 in WB 和 IF (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1390391
发货至: 中国

Quick Overview for HAS2 抗体 (AbBy Fluor® 555) (ABIN1390391)

抗原

See all HAS2 抗体
HAS2 (Hyaluronan Synthase 2 (HAS2))

适用

人, 小鼠, 大鼠

宿主

  • 38
  • 17

克隆类型

  • 38
  • 17
多克隆

标记

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  • 1
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  • 1
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  • 1
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This HAS2 antibody is conjugated to AbBy Fluor® 555

应用范围

  • 39
  • 22
  • 20
  • 11
  • 10
  • 9
  • 9
  • 6
  • 4
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human HAS2/Hyaluronan synthase 2

    亚型

    IgG
  • 应用备注

    IF(IHC-P): (1:50-200)
    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    HAS2 (Hyaluronan Synthase 2 (HAS2))

    别名

    Has2

    背景

    Synonyms: HA synthase 2, has2, HAS2_HUMAN, Hyaluronan synthase 2, Hyaluronate synthase 2, Hyaluronic acid synthase 2.

    Background: HAS1, HAS2 and HAS3 are HA Synthase proteins that synthesize HA (Hyaluronan or hyaluronic acid). The extracellular matrix in most vertebrates express HA, which is a high molecular weight linear polysaccharide composed of alternating glucuronic acid and N-acetylglucosamine residues linked by i²-1,3 and i²-1,4 glycosidic bonds. The three HAS genes show distinct patterns of expression during development and their protein products play significantly different roles in the formation of the HA matrix. Both HAS1 and HAS2 synthesise high molecular-weight HA, whereas HAS3 produces lower molecular weight HA. The expression of the three HAS isoforms is more prominent in growing cells than in resting cells and is differentially regulated by various stimuli suggesting distinct functional roles of the three proteins. HAS2 mRNA shows predominant expression in chondrocytes and cartilage. The human HAS2 gene maps to chromosome 8q24.12.

    途径

    Glycosaminoglycan Metabolic Process
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