RAB11A 抗体 (AbBy Fluor® 350)
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北京 101111
Quick Overview for RAB11A 抗体 (AbBy Fluor® 350) (ABIN1390203)
抗原
See all RAB11A 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rab11A Polyclonal Antibody, AbBy Fluor-350 Conjugated
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Rab11A
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亚型
- IgG
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应用备注
- WB(1:500-2000), IF(1:100-500)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- RAB11A (RAB11A, Member RAS Oncogene Family (RAB11A))
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别名
- Rab11a
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背景
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Synonyms: Rab 11, Rab11A, Rab-11A, RAB 11A member oncogene family, Rab-11, RAB11 A, RAB11, RAB11A, RAB11A member RAS oncogene family, Ras related protein Rab 11A, Ras related protein Rab11A, Ras-related protein Rab-11A, RB11A_HUMAN, YL 8, YL8, MGC1490.
Background: Rab11a, Rab11b and Rab25 are members of the Rab11 family of small Ras-like GTPases. Rab11 (isoforms Rab11a and Rab11b) functions as a key regulator in the recycling of perinuclear, plasma membrane and Golgi compartment endosomes (1,2). Despite some overlap, distinct differences exist between Rab11a and Rab11b in both their cellular distribution and functional roles. Rab11a is ubiquitously expressed while Rab11b is found mainly in the heart and brain (3,4). Like other Rab proteins, Rab11 exerts its function via interactions with Rab11 family interacting proteins (FIPs). While there are three distinct classes of FIPs, all appear to share a conserved carboxy-terminal Rab-binding domain that allows Rab-FIP protein interaction. When bound together, these proteins are thought to regulate membrane-associated protein sorting (5,6).
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途径
- Regulation of Cell Size, Thromboxane A2 Receptor Signaling, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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