EPH Receptor B1 抗体 (pTyr928) (AbBy Fluor® 488)
Quick Overview for EPH Receptor B1 抗体 (pTyr928) (AbBy Fluor® 488) (ABIN1388620)
抗原
See all EPH Receptor B1 (EPHB1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr928
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human EphB1 around the phosphorylation site of Tyr928
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亚型
- IgG
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anti-EPH Receptor B1 (EPHB1) (AA 955-984), (C-Term) antibody
EPHB1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1648 unconjugated
anti-EPH Receptor B1 (EPHB1) (AA 221-320) antibodyEPHB1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G6 unconjugated
anti-EPH Receptor B1 (EPHB1) (pTyr594), (pTyr604) antibodyEPHB1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B1 (EPHB1) (AA 374-409) antibodyEPHB1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB50839 unconjugated
anti-EPH Receptor B1 (EPHB1) (AA 260-500) antibodyEPHB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B1 (EPHB1) (AA 485-497), (Extracellular) antibodyEPHB1 适用: 小鼠 WB, IF, FACS, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B1 (EPHB1) (pTyr928) antibodyEPHB1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B1 (EPHB1) (C-Term) antibodyEPHB1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B1 (EPHB1) (AA 260-500) antibodyEPHB1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B1 (EPHB1) (AA 620-1596) antibodyEPHB1 适用: 人 WB, IHC, IP 宿主: 绵羊 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- EPH Receptor B1 (EPHB1)
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别名
- Eph receptor B1
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背景
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Synonyms: ELK, NET, Hek6, EPHT2, Ephrin type-B receptor 1, EPH tyrosine kinase 2, EPH-like kinase 6, EK6, Neuronally-expressed EPH-related tyrosine kinase, Tyrosine-protein kinase receptor EPH-2, EPHB1
Background: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Cognate/functional ephrin ligands for this receptor include EFNB1, EFNB2 and EFNB3. During nervous system development, regulates retinal axon guidance redirecting ipsilaterally ventrotemporal retinal ganglion cells axons at the optic chiasm midline. This probably requires repulsive interaction with EFNB2. In the adult nervous system together with EFNB3, regulates chemotaxis, proliferation and polarity of the hippocampus neural progenitors. In addition to its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and synapse formation. May also regulate angiogenesis. More generally, may play a role in targeted cell migration and adhesion. Upon activation by EFNB1 and probably other ephrin-B ligands activates the MAPK/ERK and the JNK signaling cascades to regulate cell migration and adhesion respectively.
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基因ID
- 2047
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UniProt
- P54762
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途径
- RTK signaling
抗原
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