ESR2 抗体 (pSer87)
Quick Overview for ESR2 抗体 (pSer87) (ABIN1387942)
抗原
See all ESR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer87
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Sheep,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human Estrogen Receptor beta around the phosphorylation site of Ser87 [HL(p-S)PL]
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- ESR2 (Estrogen Receptor 2 (ESR2))
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别名
- Estrogen Receptor beta
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背景
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Synonyms: Estrogen Receptor beta phospho S87, Estrogen Receptor beta phospho Ser87, p-ER betaS87, p-ER betaSer87, ER-betaSer87, ER-betaS87, Estrogen receptor-beta, ER BETA, ER-BETA, ER-beta, Erb, ESR 2, ESR 2, ESR B, ESR-B, ESR BETA, ESR-BETA, ESR2, ESR2, ESR2_HUMAN, ESRB, ESTRB, estrogen nuclear receptor beta variant a, estrogen nuclear receptor beta variant b, estrogen receptor 2 ER beta, Estrogen Receptor 2, Estrogen Receptor-2, estrogen receptor beta 4, Estrogen receptor beta, NR3A2, Nuclear receptor subfamily 3 group A member 2.
Background: Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ER alpha and ER beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. ER alpha and ER beta A have been shown to be differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ER alpha and ER beta may be regulated by distinct mechanisms even though they share many functional characteristics.
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基因ID
- 2100
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途径
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
抗原
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