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MSH3 抗体 (AA 521-620)

This anti-MSH3 antibody is a 兔 多克隆 antibody detecting MSH3 in WB, IHC (p) 和 IHC (fro). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1387851
发货至: 中国

Quick Overview for MSH3 抗体 (AA 521-620) (ABIN1387851)

抗原

See all MSH3 抗体
MSH3 (MutS Homolog 3 (MSH3))

适用

人, 小鼠, 大鼠

宿主

  • 27

克隆类型

  • 27
多克隆

标记

  • 13
  • 1
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  • 1
  • 1
  • 1
  • 1
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This MSH3 antibody is un-conjugated

应用范围

  • 13
  • 13
  • 11
  • 9
  • 5
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  • 2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 15
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 521-620

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Cow,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human MSH3

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    MSH3 (MutS Homolog 3 (MSH3))

    别名

    MSH3

    背景

    Synonyms: DUP, MRP1, DNA mismatch repair protein Msh3, hMSH3, Divergent upstream protein, Mismatch repair protein 1, MSH3, DUC1, DUG

    Background: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.

    基因ID

    4437

    UniProt

    P20585

    途径

    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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