KCNJ11 抗体 (pThr224)
Quick Overview for KCNJ11 抗体 (pThr224) (ABIN1387772)
抗原
See all KCNJ11 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr224
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human Kir6.2 around the phosphorylation site of Thr224
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亚型
- IgG
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anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (AA 172-390) antibody
KCNJ11 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (AA 301-390) antibodyKCNJ11 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (Internal Region) antibodyVerified KCNJ11 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (AA 190-239) antibodyKCNJ11 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (Center) antibodyKCNJ11 适用: 人, 小鼠, 大鼠, 兔, Cow, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (AA 372-385), (Intracellular) antibodyKCNJ11 适用: 大鼠 WB, IHC, IF 宿主: 豚鼠 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (Ser688) antibodyKCNJ11 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (AA 171-390) antibodyKCNJ11 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (AA 1-30), (N-Term) antibodyKCNJ11 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB21238 unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (AA 372-385), (Intracellular) antibodyKO Validated KCNJ11 适用: 大鼠 WB, IHC, IF, FACS, IC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- KCNJ11 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))
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别名
- Kir6.2
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背景
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Synonyms: p-Kir6.2 phospho T224, ATP sensitive inward rectier potassium channel 11, Beta cell inward rectier subunit, mBIR, BIR, HHF 2, HHF2, IKATP, Inward rectier K+ channel Kir6.2, Inwardly rectying potassium channel KIR6.2, IRK 11, IRK11, KCNJ11, Kir 6.2, Kir6.2, MGC133230, PHHI, Potassium channel, inwardly rectying subfamily J member 11, Potassium inwardly rectying channel J11, TNDM 3, TNDM3.
Background: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq]
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途径
- Negative Regulation of Hormone Secretion
抗原
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