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NCAM2 抗体 (AA 51-150)

This anti-NCAM2 antibody is a 兔 多克隆 antibody detecting NCAM2 in ELISA 和 FACS. Suitable for 人.
产品编号 ABIN1387627
发货至: 中国

Quick Overview for NCAM2 抗体 (AA 51-150) (ABIN1387627)

抗原

See all NCAM2 抗体
NCAM2 (Neural Cell Adhesion Molecule 2 (NCAM2))

适用

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宿主

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克隆类型

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多克隆

标记

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This NCAM2 antibody is un-conjugated

应用范围

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ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    AA 51-150

    交叉反应

    预测反应

    Mouse,Rat,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human NCAM2

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    FCM 1:20-100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    NCAM2 (Neural Cell Adhesion Molecule 2 (NCAM2))

    别名

    NCAM2

    背景

    Synonyms: N CAM 2, N CAM 21, N CAM2, N CAM21, N-CAM-2, NCAM 2, NCAM 21, NCAM-2, Ncam2, NCAM2_HUMAN, NCAM21, Neural cell adhesion molecule 2, OCAM GPI, R4B12, RB 8 neural cell adhesion molecule, RB8 neural cell adhesion molecule, RNCAM.

    Background: NCAM2 is an 837 amino acid protein encoded by the human gene NCAM2. NCAM2 contains five immunoglobulin-like domains, two Fibronectin type III domains, a transmembrane domain and a cytoplasmic domain. The gene is expressed most strongly in human adult and fetal brain. NCAM2 is a member of the neural cell adhesion molecule (NCAM) family. NCAMs are closely related cell surface glycoproteins involved in cell to cell interactions during growth and are thought to play an important role in embryogenesis and development. NCAM2 is a considered a good candidate for involvement in certain Down syndrome phenotypes because a slight overexpression of NCAMs increases many-fold the homotypic adhesion properties of cells. Stat5 regulates NCAM2 in vivo by binding to the NCAM2 intron in the NKL natural killer cell line, this binding is induced by cytokines that activate Stat5. Neither Stat1 nor Stat3 bind to this region, despite sharing a consensus binding sequence with Stat5.

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