NCAM2 抗体 (Extracellular, N-Term)
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Quick Overview for NCAM2 抗体 (Extracellular, N-Term) (ABIN7043352)
抗原
See all NCAM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 635-650, Extracellular, N-Term
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原理
- A Rabbit Polyclonal Antibody to Neural Cell Adhesion Molecule 2
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Rat,human - identical
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产品特性
- Anti-NCAM2 (extracellular) Antibody (ABIN7043352, ABIN7044688 and ABIN7044689) is a highly specific antibody directed against mouse Neural cell adhesion molecule 2. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize NCAM2 from rat, mouse, and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)KEDQWLEKKVQGNKDH, corresponding to amino acid residues 635-650 of mouse NCAM-2
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亚型
- IgG
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anti-Neural Cell Adhesion Molecule 2 (NCAM2) (AA 21-297) antibody
NCAM2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neural Cell Adhesion Molecule 2 (NCAM2) (C-Term) antibodyVerified NCAM2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Neural Cell Adhesion Molecule 2 (NCAM2) (AA 209-333) antibodyNCAM2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neural Cell Adhesion Molecule 2 (NCAM2) (AA 598-695) antibodyNCAM2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Neural Cell Adhesion Molecule 2 (NCAM2) (Internal Region) antibodyNCAM2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neural Cell Adhesion Molecule 2 (NCAM2) (AA 1-837) antibodyNCAM2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Neural Cell Adhesion Molecule 2 (NCAM2) (AA 575-624) antibodyNCAM2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 猴, Bat, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Neural Cell Adhesion Molecule 2 (NCAM2) (AA 620-649) antibodyNCAM2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB40145 unconjugated
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应用备注
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WB: 1:200
FC: 2.5 μg per reaction
ICC: The optimal concentration should be determined by the user
IHC: The optimal concentration should be determined by the user
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7236022)
Blocking Peptide: (ABIN7236022)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- NCAM2 (Neural Cell Adhesion Molecule 2 (NCAM2))
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别名
- NCAM2
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背景
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Synonyms: Neural cell adhesion molecule 2, NCAM-2, R4B12, Ocam, Rncam, NCAM21, Neural cell adhesion molecule RB-8
Description: Neural cell adhesion molecule 2 (NCAM-2), a protein also known as olfactory cell adhesion molecule (OCAM), belongs to the immunoglobulin superfamily of cell adhesion molecules that participate in homophilic trans-interactions. NCAM-2 is highly expressed in the nervous system and participates in numerous cellular events, such as survival, migration, and differentiation, neurite outgrowth, and formation and plasticity of synapses1,2. The NCAM-2 structure consists of five immunoglobulin (Ig) domains followed by two fibronectin-type 3 (Fn3) domains and eight potential sites for N-linked glycosylation3.Overexpression of NCAM-2 is believed to be a contributing factor to Down syndrome. There is also a genetic association between NCAM-2 and Alzheimer's disease, where NCAM-2 is involved in the pathogenic pathway to the senile plaques that concentrate in the Alzheimer's disease brain1.During human embryonic development, NCAM-2 is expressed in several tissues, including lung, liver, and kidney with the highest expression in the brain. NCAM-2 expression level rises around postnatal day 21 and remains high during adulthood. Studies conducted on NCAM-2 deficient mice show that the protein is important for the development of the brain and the olfactory system1.
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基因ID
- 17968
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NCBI登录号
- NM_004540
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UniProt
- O35136
抗原
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