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CXCR7 抗体 (AA 151-250)

Name: CXCR7 抗体 (AA 151-250)
SKU: ABIN1387536
Availability: OutOfStock

This anti-CXCR7 antibody is a 兔多克隆 antibody detecting CXCR7 in WB, ELISA, IHC (p), IF (cc), IF (p), ICC 和 IHC (fro). Suitable for 人和大鼠. This Primary Antibody has been cited in 2+ publications.

Formalin-fixed and paraffin embedded rat brain labeled with Anti-CXCR7/RDC1 Polyclonal Antibody, Unconjugated (ABIN1387536) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (CXCR7 抗体 (AA 151-250))

IHC

Formalin-fixed and paraffin embedded rat kidney labeled with Anti-CXCR7/RDC1 Polyclonal Antibody, Unconjugated (ABIN1387536) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (CXCR7 抗体 (AA 151-250))

IHC

2 images

(2 references)

产品编号 ABIN1387536

发货至: 中国

Datasheet as PDF

Quick Overview for CXCR7 抗体 (AA 151-250) (ABIN1387536)

抗原

See all CXCR7 抗体

CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

适用

人, 大鼠

宿主

兔

克隆类型

多克隆

标记

This CXCR7 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product CXCR7 Primary Antibody

抗原表位
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AA 151-250

交叉反应

人, 大鼠

预测反应

Mouse,Dog,Cow,Pig,Horse,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human CXCR7/RDC1

亚型

IgG
anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) antibody
KO Validated CXCR7 适用: 人 WB, ELISA, FACS, IF, IHC (p), IP, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) antibody
CXCR7 适用: 人, 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (Internal Region) antibody
CXCR7 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (AA 311-360) antibody
CXCR7 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (Extracellular Domain) antibody
CXCR7 适用: 人, 大鼠, 小鼠, 犬, Cow, Pig, 马, Bat, Hamster, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (Cytoplasmic Domain) antibody
CXCR7 适用: 人, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) antibody
CXCR7 适用: 人 FACS 宿主: 小鼠 Monoclonal 10D1-J16 unconjugated

anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (AA 50-150) antibody
CXCR7 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (AA 330-358), (C-Term) antibody
CXCR7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB23520 unconjugated

anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (AA 330-358) antibody
CXCR7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Cao, Song, Ge, Song, Chen, Wu: "MicroRNA-100 suppresses human gastric cancer cell proliferation by targeting CXCR7." in: Oncology letters, Vol. 15, Issue 1, pp. 453-458, (2018) (PubMed).
抗原

CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

别名

CXCR7/RDC1

背景

Synonyms: RDC1, CXCR7, RDC-1, CMKOR1, CXC-R7, CXCR-7, GPR159, Atypical chemokine receptor 3, C-X-C chemokine receptor type 7, Chemokine orphan receptor 1, G-protein coupled receptor 159, G-protein coupled receptor RDC1 homolog, ACKR3
Background: Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. Chemokine binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalization and activation of MAPK signaling pathway. Required for regulation of CXCR4 protein levels in migrating interneurons, thereby adapting their chemokine responsiveness. In glioma cells, transduces signals via MEK/ERK pathway, mediating resistance to apoptosis. Promotes cell growth and survival. Not involved in cell migration, adhesion or proliferation of normal hematopoietic progenitors but activated by CXCL11 in malignant hemapoietic cells, leading to phosphorylation of ERK1/2 (MAPK3/MAPK1) and enhanced cell adhesion and migration. Plays a regulatory role in CXCR4-mediated activation of cell surface integrins by CXCL12. Required for heart valve development. Acts as coreceptor with CXCR4 for a restricted number of HIV isolates.

基因ID

57007

UniProt

P25106

途径

Myometrial Relaxation and Contraction, Negative Regulation of intrinsic apoptotic Signaling