电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

UBE2N 抗体 (AA 56-152)

This anti-UBE2N antibody is a 兔 多克隆 antibody detecting UBE2N in ELISA, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 大鼠 和 小鼠.
产品编号 ABIN1387434
发货至: 中国

Quick Overview for UBE2N 抗体 (AA 56-152) (ABIN1387434)

抗原

See all UBE2N 抗体
UBE2N (Ubiquitin-Conjugating Enzyme E2N (UBE2N))

适用

  • 35
  • 35
  • 33
  • 6
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
大鼠, 小鼠

宿主

  • 44
  • 4
  • 1

克隆类型

  • 36
  • 13
多克隆

标记

  • 24
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This UBE2N antibody is un-conjugated

应用范围

  • 22
  • 17
  • 12
  • 12
  • 10
  • 7
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 56-152

    交叉反应

    小鼠, 大鼠

    预测反应

    Human,Dog,Cow,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Ube2N/UBC13

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    UBE2N (Ubiquitin-Conjugating Enzyme E2N (UBE2N))

    别名

    Ube2N

    背景

    Synonyms: UBC 13, UBC13, UbCH ben, Ube 2N, Ube2n, UBE2N_HUMAN, ubiquitin carrier protein N, Ubiquitin conjugating enzyme E2 N, Ubiquitin conjugating enzyme E2N homologous to yeast UBC13, Ubiquitin conjugating enzyme E2N UBC13 homolog yeast, Ubiquitin conjugating enzyme E2N, ubiquitin protein ligase N, Ubiquitin-conjugating enzyme E2 N, ubiquitin-conjugating enzyme E2N homologous to yeast UBC13, ubiquitin-conjugating enzyme E2N UBC13 homolog yeast, Ubiquitin-protein ligase N, Yeast UBC13 homolog, bendless like ubiquitin conjugating enzyme, Bendless-like ubiquitin-conjugating enzyme, BLU, EC 6.3.2.19, Human epidermoid carcinoma mRNA for ubiquitin-conjugating enzyme E2 similar to Drosophila bendless gene product complete cds, MGC131857, MGC8489.

    Background: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). UBC13, also known as UBE2N or BLU, is a 152 amino acid member of the E2 ubiquitin-conjugating enzyme family. Existing as a heterodimer with Mms2 (also known as UBE2V2), UBC13 catalyzes the ATP-dependent synthesis of non-canonical polyubiquitin chains, a process that does not lead to proteasomal degradation. Additionally, UBC13 mediates the transcription of several target genes and is thought to play a role in cell cycle progression, cellular differentiation and DNA repair mechanisms that ensure cell survival after DNA damage.

    基因ID

    7334

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Positive Regulation of Response to DNA Damage Stimulus, Ubiquitin Proteasome Pathway
You are here:
Chat with us!