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tau 抗体 (pThr181)

This anti-tau antibody is a 兔 多克隆 antibody detecting tau in WB, ELISA, IF (cc) 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1387422
发货至: 中国

Quick Overview for tau 抗体 (pThr181) (ABIN1387422)

抗原

See all tau 抗体
tau (tau Protein)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This tau antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    pThr181

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human Tau protein around the phosphorylation site of Thr181

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    tau (tau Protein)

    背景

    Synonyms: TauThr181, MAPTphospho T181, p-TauThr181, MAPT, Microtuble-associted protein Tau, AI413597, AW045860, DDPAC, Disinhibition dementia parkinsonism amyotrophy complex, FLJ31424, FTDP 17, FTDP17, G Protein beta 1 gamma 2 subunit interacting factor 1, G protein beta1/gamma2 subunit interacting factor 1, MAPTL, MGC134287, MGC138549, MGC156663, Microtubule associated protein tau isoform 4, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, Paired helical filament tau, PHF tau, PHF-tau, PPND, pTau, RNPTAU, Tauopathy and respiratory failure, included, TAU_HUMAN.

    Background: Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.

    分子量

    83kDa

    基因ID

    4137
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