ATRIP 抗体
Quick Overview for ATRIP 抗体 (ABIN1387408)
抗原
See all ATRIP 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ATRIP
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亚型
- IgG
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anti-ATR Interacting Protein (ATRIP) (AA 42-309) antibody
ATRIP 适用: 人, 犬 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 5E7 unconjugated
anti-ATR Interacting Protein (ATRIP) (N-Term) antibodyATRIP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATR Interacting Protein (ATRIP) (pSer224) antibodyATRIP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATR Interacting Protein (ATRIP) (pSer68) antibodyATRIP 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATR Interacting Protein (ATRIP) (AA 1-260) antibodyATRIP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-ATR Interacting Protein (ATRIP) (AA 1-260) antibodyATRIP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATR Interacting Protein (ATRIP) antibodyATRIP 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATR Interacting Protein (ATRIP) (Tyr783) antibodyATRIP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATR Interacting Protein (ATRIP) (pSer224) antibodyATRIP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATR Interacting Protein (ATRIP) (AA 42-309) antibodyATRIP 适用: 人 WB 宿主: 小鼠 Monoclonal 1G6 unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- ATRIP (ATR Interacting Protein (ATRIP))
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别名
- ATRIP/TREX1
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背景
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Synonyms: AGS 1, AGS1, AGS-1, Aicardi Goutieres syndrome 1, ATIP, ATM and Rad3 related interacting protein, ATM and Rad3-related-interacting protein, ATR interacting protein, ATR-interacting protein, Atrip, ATRIP_HUMAN, Deoxyribonuclease III dnaQ/mutD E. coli like, DKFZp434J0310, DKFZp762J2115, DNase III, DRN 3, DRN3, FLJ12343, MGC20625, MGC26740, Three prime repair exonuclease 1, TREX 1, TREX1, TREX1 protein, MGC21482, 3' repair exonuclease 1, 3'-5' exonuclease TREX1.
Background: DNA damage or incomplete replication of DNA results in the inhibition of cell cycle progression at the G1 to S or the G2 to M phase transition by conserved regulatory mechanisms known as cell cycle checkpoints. Checkpoint proteins include Rad17, which is involved in regulating cell cycle progression at the G1 checkpoint as well as Chk1, Chk2, Rad1, Rad9 and Hus1, which are involved in regulating cell cycle arrest at the G2 checkpoint. In response to DNA damage, ATM and ATR kinases are important for cell cycle checkpoint response signalling. ATR-interacting protein (ATRIP), also designated ATM and Rad3-related-interacting protein, is required for checkpoint signaling after DNA damage. It is also important for ATR expression, which regulates DNA replication and damage checkpoint responses. ATRIP is a ubiquitously expressed protein that can form heterodimers with ATR. After dimerization they bind the RPA complex and are recruited to single stranded DNA. ATRIP is a nuclear protein that may also play a role in protein stabilization.
抗原
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