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UGCG 抗体 (AA 31-98)

This anti-UGCG antibody is a 兔 多克隆 antibody detecting UGCG in WB 和 ELISA. Suitable for 小鼠 和 大鼠.
产品编号 ABIN1386872
发货至: 中国

Quick Overview for UGCG 抗体 (AA 31-98) (ABIN1386872)

抗原

See all UGCG 抗体
UGCG (UDP-Glucose Ceramide Glucosyltransferase (UGCG))

适用

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  • 31
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  • 1
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小鼠, 大鼠

宿主

  • 42
  • 2

克隆类型

  • 43
  • 1
多克隆

标记

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  • 1
  • 1
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This UGCG antibody is un-conjugated

应用范围

  • 31
  • 14
  • 14
  • 10
  • 6
  • 6
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  • 5
  • 3
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 16
    • 4
    • 4
    • 2
    • 1
    • 1
    AA 31-98

    交叉反应

    小鼠, 大鼠

    预测反应

    Human,Dog,Cow,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human UGCG

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    UGCG (UDP-Glucose Ceramide Glucosyltransferase (UGCG))

    别名

    UGCG

    背景

    Synonyms: CEGT_HUMAN, Ceramide glucosyltransferase, GCS, GLCT 1, GLCT-1, GLCT1, Glucosylceramide synthase, UDP glucose ceramide glucosyltransferase, UDP glucose N acylsphingosine D glucosyltransferase, UDP-glucose ceramide glucosyltransferase, UDP-glucose:N-acylsphingosine D-glucosyltransferase, Ugcg.

    Background: Glucosylceramide synthase (GCS), also designated ceramide glucosyltransferase, belongs to the glycosyltransferase 2 family. It is a widely expressed integral membrane protein encoded by UGCG. The enzyme can be found in the plasma membrane of all eukaryotic cells, and a significant concentration of glucosylceramide synthase activity has been reported in the Golgi complex. Glucosylceramide synthase catalyzes the first glycosylation step in glycosphingolipid biosynthesis and functions as a glucosyltransferase and flippase in the transfer of glucose to ceramide. Glucosylceramide synthase operates in cell recognition, cell proliferation and differentiation, immune recognition and signal transduction. The regulation of ceramide levels through glucosylceramide synthase has been associated with the induction of apoptosis and notable research implicates this relationship with drug-induced apoptosis in a variety of cell types.

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