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PMS1 抗体 (AA 245-350)

PMS1 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386867
发货至: 中国
  • 抗原 See all PMS1 抗体
    PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))
    抗原表位
    • 15
    • 14
    • 9
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 245-350
    适用
    • 67
    • 13
    • 5
    宿主
    • 62
    • 4
    • 1
    克隆类型
    • 64
    • 3
    多克隆
    标记
    • 22
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PMS1 antibody is un-conjugated
    应用范围
    • 41
    • 27
    • 25
    • 25
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    预测反应
    Human,Mouse,Rat,Cow,Sheep,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human PMS1
    亚型
    IgG
    Top Product
    Discover our top product PMS1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))
    别名
    PMS1 (PMS1 产品)
    别名
    PMSL1 antibody, si:dz72b14.2 antibody, si:dz164h20.2 antibody, PMS1 antibody, DKFZp468M105 antibody, pms1 antibody, HNPCC3 antibody, hPMS1 antibody, PMS1 homolog 1, mismatch repair system component antibody, PMS1 homolog 1, mismatch repair system component S homeolog antibody, PMS1 antibody, Pms1 antibody, pms1 antibody, pms1.S antibody
    背景

    Synonyms: DNA mismatch repair protein PMS1, HNPCC3, hPMS1, Human homolog of yeast mutL, Mismatch repair gene PMSL1, pms1, PMS1 postmeiotic segregation increased 1 S. cerevisiae, PMS1 postmeiotic segregation increased 1, PMS1 protein homolog 1, PMS1_HUMAN, PMSL1, Rhabdomyosarcoma antigen MU RMS 40.10B, Rhabdomyosarcoma antigen MU RMS 40.10E.

    Background: The finding that mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) has resulted in considerable interest in the understanding of the mechanism of DNA mismatch repair. Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes MutS and MutL were demonstrated at high frequency in HNPCC and were shown to be associated with microsatellite instability. The demonstration that 10 to 45 % of pancreatic, gastric, breast, ovarian and small cell lung cancers also display microsatellite instability has been interpreted to suggest that DNA mismatch repair is not restricted to HNPCC tumors but is a common feature in tumor initiation or progression. Two additional homologs of the prokaryotic MutL gene, designated PMS1 and PMS2, have been identified and shown to be mutated in the germline of HNPCC patients.

    基因ID
    5378
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