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FBXW4 抗体 (AA 171-270)

This anti-FBXW4 antibody is a 兔 多克隆 antibody detecting FBXW4 in ELISA 和 IHC (p). Suitable for 大鼠.
产品编号 ABIN1386820
发货至: 中国

Quick Overview for FBXW4 抗体 (AA 171-270) (ABIN1386820)

抗原

See all FBXW4 抗体
FBXW4 (F-Box and WD Repeat Domain Containing 4 (FBXW4))

适用

  • 39
  • 22
  • 21
  • 5
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
大鼠

宿主

  • 39
  • 2

克隆类型

  • 41
多克隆

标记

  • 15
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FBXW4 antibody is un-conjugated

应用范围

  • 22
  • 21
  • 12
  • 8
  • 3
  • 3
  • 2
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 9
    • 9
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 171-270

    交叉反应

    大鼠

    预测反应

    Human,Mouse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human SHFM3

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-P 1:200-400

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    FBXW4 (F-Box and WD Repeat Domain Containing 4 (FBXW4))

    别名

    SHFM3

    背景

    Synonyms: DAC, Dactylin, F box and WD 40 domain containing protein 4, F box and WD 40 domain protein 4, F box and WD repeat domain containing 4, F box/WD repeat containing protein 4, F box/WD repeat protein 4, F-box and WD-40 domain-containing protein 4, F-box/WD repeat-containing protein 4, FBW 4, FBW4, FBWD 4, FBWD4, FBXW 4, FBXW4, FBXW4_HUMAN, SHFM 3, SHSF 3, SHSF3, Split hand/foot malformation ectrodactyly type.

    Background: Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling.Involvement in disease:Defects in FBXW4 are a cause of split-hand/foot malformation type 3 (SHFM3) . SHFM3 is an autosomal dominant disorder characterized by hypoplasia/aplasia of the central digits with fusion of the remaining digits.

    基因ID

    6468
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