Caspase 1 p20 抗体 (AA 188-290)
(1 reference)Quick Overview for Caspase 1 p20 抗体 (AA 188-290) (ABIN1386773)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 188-290
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Caspase-1 p20
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亚型
- IgG
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anti-Caspase 1 p20 (AA 181-280) antibody
适用: 人, 小鼠, 大鼠 WB, FACS, IF (cc), IF (p), ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 1 p20 antibody适用: 小鼠 WB, IP, IHC 宿主: 小鼠 Monoclonal Casper-1 unconjugated
anti-Caspase 1 p20 antibody适用: 人 WB 宿主: 小鼠 Monoclonal Bally-1 unconjugated
anti-Caspase 1 p20 (AA 101-200) antibody适用: 人, 小鼠, 大鼠 WB, FACS, IF (cc), IF (p), ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Cortistatin inhibits NLRP3 inflammasome activation of cardiac fibroblasts during sepsis." in: Journal of cardiac failure, (2015) (PubMed).
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: "Cortistatin inhibits NLRP3 inflammasome activation of cardiac fibroblasts during sepsis." in: Journal of cardiac failure, (2015) (PubMed).
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- Caspase 1 p20
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别名
- Caspase-1 P20
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背景
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Synonyms: caspase-1 isoform alpha p20 subunit,CASP 1, CASP1, Caspase 1 apoptosis related cysteine peptidase, Caspase 1 apoptosis related cysteine protease, Caspase1, ICE, IL 1 beta converting enzyme, IL 1BC, IL1B convertase, IL1BC, IL1BCE, Interleukin 1 beta convertase, Interleukin 1 beta convertase precursor, Interleukin 1 beta converting enzyme.CASP-1, Interleukin-1 beta convertase, IL-1BC, Interleukin-1 beta-converting enzyme, ICE, IL-1 beta-converting enzyme, p45, Caspase-1 subunit p20.
Background: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing of this gene results in five transcript variants encoding distinct isoforms. [provided by RefSeq].
抗原
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