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Caspase 1 p20 抗体 (Biotin)

适用: 小鼠 WB, IP, IHC 宿主: 小鼠 Monoclonal Casper-1 Biotin
产品编号 ABIN1169383
发货至: 中国
  • 抗原 See all Caspase 1 p20 products
    Caspase 1 p20
    适用
    • 51
    • 33
    • 32
    小鼠
    宿主
    • 49
    • 3
    小鼠
    克隆类型
    • 49
    • 3
    单克隆
    标记
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This Caspase 1 p20 antibody is conjugated to Biotin
    应用范围
    • 42
    • 36
    • 26
    • 26
    • 10
    • 9
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
    特异性
    Recognizes endogenous full-length and activated (p20 fragment) mouse caspase-1.
    交叉反应
    小鼠
    纯化方法
    Purified from concentrated hybridoma tissue culture supernatant.
    纯度
    >95 % (SDS-PAGE)
    免疫原
    Recombinant mouse caspase-1.
    克隆位点
    Casper-1
    亚型
    IgG1
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    In PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    有效期
    12 months
  • Carpentier, Ni, Duggan, James, Cookson, Hamerman: "The signaling adaptor BCAP inhibits NLRP3 and NLRC4 inflammasome activation in macrophages through interactions with Flightless-1." in: Science signaling, Vol. 12, Issue 581, (2020) (PubMed).

  • 抗原
    Caspase 1 p20
    别名
    Caspase-1 p20 (Caspase 1 p20 产品)
    背景
    Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals.
    UniProt
    P29452
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