SLC12A6 抗体 (AA 401-500)
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- 抗原 See all SLC12A6 抗体
- SLC12A6 (Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 6 (SLC12A6))
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抗原表位
- AA 401-500
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SLC12A6 antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Cow,Sheep,Pig,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human SLC12A6/KCC3
- 亚型
- IgG
- Top Product
- Discover our top product SLC12A6 Primary Antibody
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anti-Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 6 (SLC12A6) (AA 1-90) antibody
SLC12A6 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 6 (SLC12A6) (Internal Region) antibodyVerified SLC12A6 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 6 (SLC12A6) (AA 60-190) antibodySLC12A6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 6 (SLC12A6) antibodySLC12A6 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 6 (SLC12A6) (Internal Region) antibody (Biotin)Verified SLC12A6 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal Biotin
anti-Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 6 (SLC12A6) (AA 559-735) antibodySLC12A6 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 6 (SLC12A6) (AA 13-42), (N-Term) antibodySLC12A6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB31331 unconjugated
anti-Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 6 (SLC12A6) (C-Term) antibodySLC12A6 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- SLC12A6 (Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 6 (SLC12A6))
- 别名
- SLC12A6/KCC3 (SLC12A6 产品)
- 别名
- Kcc3 antibody, ACCPN antibody, KCC3 antibody, KCC3A antibody, KCC3B antibody, 9530023I19Rik antibody, gaxp antibody, solute carrier family 12, member 6 antibody, solute carrier family 12 member 6 antibody, Slc12a6 antibody, SLC12A6 antibody
- 背景
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Synonyms: ACCPN, Furosemide sensitive KCl cotransporter 3, Gaxp, KCC 3, KCC 3A, KCC 3B, KCC3 A, KCC3, KCC3 B, KCC3A, KCC3B, Potassium chloride cotransporter 3, Potassium chloride cotransporter KCC3a S3, SLC12 A6, SLC12A 6, Solute carrier family 12 potassium/chloride transporters, member 6, Solute carrier family 12, member 6, S12A6_HUMAN.
Background: The four isoforms of potassium/chloride co-transport channels (KCC) belong to a superfamily of cation-chloride co-transporters involved in cell volume maintenance. Nitric oxide (NO) donors activate KCCs, while inhibitors of the cGMP pathway prevent NO donor activation. The ubiquitously expressed KCC1 contains 12 transmembrane domains with both cytoplasmic N and C terminal domains. KCC2 expression is limited to neuronal tissues by a restrictive element similar to the neuronal-restrictive silencing factor. In neurons, KCC2 expression is correlated with an inhibitory response to GABA, while the absence of KCC2 is necessary for an unusual excitatory response to GABA. Alterations of KCC2 expression in the inferior colliculus of rat brain may be related to seizure susceptibility. Conversely, KCC3 is not suspected to play a major role in epilepsy. The two splice variants of KCC3, KCC3a and KCC3b, are predominantly expressed in brain and kidney, respectively, while KCC4 is expressed in muscle, brain, lung, heart and kidney.
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