SLC12A6
适用: 人
IF (cc), IF (p)
宿主: 兔
Polyclonal
Alexa Fluor 488
应用备注
The stated application concentrations are suggested starting amounts. Titration of the SLC12A6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
限制
仅限研究用
缓冲液
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
储存条件
-20 °C
储存方法
After reconstitution, the SLC12A6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
抗原
SLC12A6
(Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 6 (SLC12A6))
Kcc3 antibody, ACCPN antibody, KCC3 antibody, KCC3A antibody, KCC3B antibody, 9530023I19Rik antibody, gaxp antibody, solute carrier family 12, member 6 antibody, solute carrier family 12 member 6 antibody, Slc12a6 antibody, SLC12A6 antibody
背景
Solute carrier family 12 (potassium/chloride transporters) member 6, also called KCC3, is a protein that in humans is encoded by the SLC12A6 gene. This gene is a member of the K-Cl cotransporter(KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. By radiation hybrid and somatic cell hybrid analyses, this gene is mapped to 15q14. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy.