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ABLIM3 抗体 (AA 401-500)

ABLIM3 适用: 人 ELISA, WB, IF (p), IF (cc), IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386608
发货至: 中国
  • 抗原 See all ABLIM3 抗体
    ABLIM3 (Actin Binding LIM Protein Family, Member 3 (ABLIM3))
    抗原表位
    • 15
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    AA 401-500
    适用
    • 31
    • 23
    • 8
    宿主
    • 44
    • 2
    克隆类型
    • 46
    多克隆
    标记
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    This ABLIM3 antibody is un-conjugated
    应用范围
    • 20
    • 19
    • 13
    • 13
    • 3
    • 3
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    预测反应
    Human,Mouse,Rat,Cow,Sheep,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human ABLIM3
    亚型
    IgG
    Top Product
    Discover our top product ABLIM3 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    ABLIM3 (Actin Binding LIM Protein Family, Member 3 (ABLIM3))
    别名
    ABLIM3 (ABLIM3 产品)
    别名
    AW990719 antibody, D930036B08Rik antibody, RGD1565118 antibody, actin binding LIM protein family member 3 antibody, actin binding LIM protein family, member 3 antibody, ABLIM3 antibody, Ablim3 antibody
    背景

    Synonyms: abLIM-3, Ablim3, ABLM3_HUMAN, Actin binding LIM protein 3, Actin binding LIM protein family member 3, Actin-binding LIM protein 3, Actin-binding LIM protein family member 3, HMFN1661, KIAA0843.

    Background: The C. elegans protein Unc-115 mediates axon guidance by modulating the growth cone Actin cytoskeleton in response to signals received by growth cone receptors. The mammalian homolog of Unc-115 is the Actin-binding LIM protein family member 1 (ABLIM1, also designated Limatin). The ABLIM1 protein has an N-terminal domain that contains four double zinc finger motifs, which conform to the LIM motif consensus sequence. ABLIM1 binds to F-Actin through a dematin-like domain and is expressed in retina, brain and muscle tissue. There are four known isoforms of ABLIM1. The gene encoding ABLIM1 maps to a region of chromosome 10 associated with frequent loss of heterozygosity in human tumors, thus identifying ABLIM1 as a candidate tumor suppressor gene. ABLIM2 and ABLIM3 show highest expression in muscle and neuronal tissues, bind to F-Actin, and are localized on stress fibers. They also have been shown to enhance STARS (striated muscle activator of Rho signaling) dependent activation of serum-response factor (SRF), thereby modulating transcription.

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