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ABLIM3 抗体 (AA 401-500)

This anti-ABLIM3 antibody is a 兔 多克隆 antibody detecting ABLIM3 in ELISA, WB, IF (cc), IF (p), IHC (fro), IHC (p) 和 ICC. Suitable for 人.
产品编号 ABIN1386608
发货至: 中国

Quick Overview for ABLIM3 抗体 (AA 401-500) (ABIN1386608)

抗原

See all ABLIM3 抗体
ABLIM3 (Actin Binding LIM Protein Family, Member 3 (ABLIM3))

适用

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宿主

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克隆类型

  • 42
多克隆

标记

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This ABLIM3 antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
  • 抗原表位

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    AA 401-500

    预测反应

    Human,Mouse,Rat,Cow,Sheep,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human ABLIM3

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    ABLIM3 (Actin Binding LIM Protein Family, Member 3 (ABLIM3))

    别名

    ABLIM3

    背景

    Synonyms: abLIM-3, Ablim3, ABLM3_HUMAN, Actin binding LIM protein 3, Actin binding LIM protein family member 3, Actin-binding LIM protein 3, Actin-binding LIM protein family member 3, HMFN1661, KIAA0843.

    Background: The C. elegans protein Unc-115 mediates axon guidance by modulating the growth cone Actin cytoskeleton in response to signals received by growth cone receptors. The mammalian homolog of Unc-115 is the Actin-binding LIM protein family member 1 (ABLIM1, also designated Limatin). The ABLIM1 protein has an N-terminal domain that contains four double zinc finger motifs, which conform to the LIM motif consensus sequence. ABLIM1 binds to F-Actin through a dematin-like domain and is expressed in retina, brain and muscle tissue. There are four known isoforms of ABLIM1. The gene encoding ABLIM1 maps to a region of chromosome 10 associated with frequent loss of heterozygosity in human tumors, thus identifying ABLIM1 as a candidate tumor suppressor gene. ABLIM2 and ABLIM3 show highest expression in muscle and neuronal tissues, bind to F-Actin, and are localized on stress fibers. They also have been shown to enhance STARS (striated muscle activator of Rho signaling) dependent activation of serum-response factor (SRF), thereby modulating transcription.

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