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FZD9 抗体 (AA 185-270)

This anti-FZD9 antibody is a 兔 多克隆 antibody detecting FZD9 in WB, ELISA, ICC 和 IF (cc). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1386280
发货至: 中国

Quick Overview for FZD9 抗体 (AA 185-270) (ABIN1386280)

抗原

See all FZD9 抗体
FZD9 (Frizzled Family Receptor 9 (FZD9))

适用

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宿主

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克隆类型

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多克隆

标记

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This FZD9 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc))
  • 抗原表位

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    AA 185-270

    特异性

    This antibody may have slight cross reactivity with Frizzled 10.

    交叉反应

    预测反应

    Mouse,Rat

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Frizzled 9/CD349

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Vasyliev, Rodnichenko, Gubar, Zlatska, Gordiienko, Novikova, Zubov: "Large-scale expansion and characterization of human adult neural crest-derived multipotent stem cells from hair follicle for regenerative medicine applications." in: Experimental oncology, Vol. 39, Issue 3, pp. 171-180, (2017) (PubMed).

  • 抗原

    FZD9 (Frizzled Family Receptor 9 (FZD9))

    别名

    Frizzled 9/CD349

    背景

    Synonyms: FZD3, CD349, Frizzled-9, Fz-9, hFz9, FzE6, FZD9

    Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

    基因ID

    8326

    UniProt

    O00144

    途径

    WNT signaling
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