APH1B 抗体 (AA 51-150)
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北京 101111
Quick Overview for APH1B 抗体 (AA 51-150) (ABIN1386275)
抗原
See all APH1B (Aph1b) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-150
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Cow,Sheep,Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Aph-1b
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亚型
- IgG
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anti-Anterior Pharynx Defective 1 Homolog B (Aph1b) (AA 93-110) antibody
Aph1b 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))
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别名
- Aph-1b
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背景
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Synonyms: PSFL, APH-1B, PRO1328, TAAV688, Gamma-secretase subunit APH-1B, Aph-1beta, Presenilin-stabilization factor-like, APH1B, UNQ688/PRO1328
Background: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Probably present in a minority of gamma-secretase complexes compared to APH1A.
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基因ID
- 83464
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UniProt
- Q8WW43
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途径
- Notch Signaling, Neurotrophin Signaling Pathway
抗原
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