GFR 抗体 (AA 151-250)
Quick Overview for GFR 抗体 (AA 151-250) (ABIN1386172)
抗原
See all GFR (RAPGEF5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 151-250
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human RAPGEF5
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亚型
- IgG
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anti-Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5) antibody
RAPGEF5 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5) (AA 201-444) antibodyRAPGEF5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5) (AA 1-444) antibodyRAPGEF5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E4 unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5) (AA 1-444) antibodyRAPGEF5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5) (C-Term) antibodyRAPGEF5 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5) (N-Term) antibodyRAPGEF5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- GFR (RAPGEF5) (Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5))
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别名
- RAPGEF5/Repac
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背景
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Synonyms: GFR, Guanine nucleotide exchange factor for Rap1, KIAA0277, M Ras regulated Rap GEF, M-Ras-regulated Rap GEF, MR GEF, MR-GEF, MRGEF, Rap guanine nucleotide exchange factor 5, Rapgef5, Related to Epac, Repac, RPGF5_HUMAN.
Background: Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as Repac, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation. Repac, also known as Rap guanine nucleotide exchange factor 5 (RAPGEF5), is a 580 amino acid protein that is expressed in brain and testis, with weaker expression in heart, placenta, lung, pancreas and small intestine. Existing as two alternatively spliced isoforms, the Repac gene is conserved in cow, mouse and rat. The gene that encodes Repac maps to human chromosome 7p15.3, with high expression of this region linking to positive response to erlotinib therapy for those with non-small-cell lung cancer.
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途径
- RTK signaling, Neurotrophin Signaling Pathway, Hepatitis C
抗原
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