TXNRD1 抗体 (AA 451-550)
Quick Overview for TXNRD1 抗体 (AA 451-550) (ABIN1386102)
抗原
See all TXNRD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 451-550
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交叉反应
 - 人, 小鼠, 大鼠
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预测反应
 - Dog,Cow,Pig,Horse
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纯化方法
 - Purified by Protein A.
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免疫原
 - KLH conjugated synthetic peptide derived from human TXNRD1
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亚型
 - IgG
 
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应用备注
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                        WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 
                                            
限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 1 μg/μL
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缓冲液
 - 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
 - ProClin
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注意事项
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
 - 12 months
 
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                                            : "Intratumoral hemorrhage-related differences in the expression of vascular endothelial growth factor, basic fibroblast growth factor and thioredoxin reductase 1 in human glioblastoma."    in: Molecular and clinical oncology, Vol. 5, Issue 4, pp. 343-346, (2016)         (PubMed).        
 
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                                            : "Intratumoral hemorrhage-related differences in the expression of vascular endothelial growth factor, basic fibroblast growth factor and thioredoxin reductase 1 in human glioblastoma."    in: Molecular and clinical oncology, Vol. 5, Issue 4, pp. 343-346, (2016)         (PubMed).        
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- TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))
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别名
 - Txnrd1
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背景
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Synonyms: TR, TR1, TXNR, TRXR1, GRIM-12, Thioredoxin reductase 1, cytoplasmic, Gene associated with retinoic and interferon-induced mortality 12 protein, Gene associated with retinoic and IFN-induced mortality 12 protein, KM-12-derived reductase-like factor, Thioredoxin reductase TR1, TXNRD1, GRIM12, KDRF
Background: Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
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基因ID
 - 7296
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UniProt
 - Q16881
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途径
 - Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis
 
抗原
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