UVRAG 抗体
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- 抗原 See all UVRAG 抗体
- UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UVRAG antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human UVRAG/DHTX
- 亚型
- IgG
- Top Product
- Discover our top product UVRAG Primary Antibody
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anti-UV Radiation Resistance Associated Gene (UVRAG) (AA 501-699) antibody
UVRAG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-UV Radiation Resistance Associated Gene (UVRAG) (AA 375-425) antibodyUVRAG 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-UV Radiation Resistance Associated Gene (UVRAG) (AA 601-699) antibodyUVRAG 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E8 unconjugated
anti-UV Radiation Resistance Associated Gene (UVRAG) antibodyUVRAG 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-UV Radiation Resistance Associated Gene (UVRAG) (C-Term) antibody (FITC)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal FITC
anti-UV Radiation Resistance Associated Gene (UVRAG) (C-Term) antibody (PE)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal PE
anti-UV Radiation Resistance Associated Gene (UVRAG) (C-Term) antibody (PerCP)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal PerCP
anti-UV Radiation Resistance Associated Gene (UVRAG) (C-Term) antibody (Atto 488)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Atto 488
anti-UV Radiation Resistance Associated Gene (UVRAG) (C-Term) antibody (Atto 594)UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Atto 594
anti-UV Radiation Resistance Associated Gene (UVRAG) (AA 666-699), (C-Term) antibodyUVRAG 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB10849 unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
- 别名
- UVRAG (UVRAG 产品)
- 别名
- DHTX antibody, VPS38 antibody, p63 antibody, 9530039D02Rik antibody, AI648770 antibody, BB124205 antibody, Uvrag1 antibody, Uvragl antibody, zgc:56164 antibody, uvrag antibody, MGC81810 antibody, UVRAG antibody, MGC131135 antibody, CG6116 antibody, Dmel\\CG6116 antibody, UV radiation resistance associated antibody, UV radiation resistance associated gene antibody, UV radiation resistance associated S homeolog antibody, UV radiation resistance associated L homeolog antibody, UV-resistance associated gene antibody, UVRAG antibody, Uvrag antibody, uvrag antibody, uvrag.S antibody, uvrag.L antibody
- 背景
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Synonyms: DHTX, Disrupted in heterotaxy, p63, UV radiation resistance associated, UV radiation resistance associated gene, UV radiation resistance associated gene protein, UV radiation resistance-associated gene protein, UVRAG, UVRAG_HUMAN.
Background: UVRAG, also known as p63 or DHTX, is a 699 amino acid cytoplasmic protein. UVRAG has been shown to activate the BECN1/PI 3-kinase complex, which promotes autophagy. Autophagy is the degradation of cellular proteins in the lysosomes, and when this pathway is suppressed, cell growth is deregulated. Mutations in the gene encoding UVRAG have been associated with colon cancer, suggesting that UVRAG is also involved in suppressing the proliferation and tumorigenicity of human colon cancer cells. UVRAG has been found to complement the ultraviolet sensitivity of xeroderma pigmentosum group C cells. Ubiquitously expressed, UVRAG is found at highest levels in kidney, lung, liver and brain. UVRAG contains one C2 domain, which is thought to be involved in calcium-dependent phospholipid binding.
- 基因ID
- 7405
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