LIG4 抗体 (AA 51-150)
Quick Overview for LIG4 抗体 (AA 51-150) (ABIN1386075)
抗原
See all LIG4 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 51-150
- 
                                            交叉反应
- 人
- 
                                            预测反应
- Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit
- 
                                            纯化方法
- Purified by Protein A.
- 
                                            免疫原
- KLH conjugated synthetic peptide derived from human DNA Ligase IV
- 
                                            亚型
- IgG
 
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    - 
                                            应用备注
- 
                        WB 1:300-5000
 ELISA 1:500-1000
 IHC-P 1:200-400
 IHC-F 1:100-500
 IF(IHC-P) 1:50-200
 IF(IHC-F) 1:50-200
 IF(ICC) 1:50-200
 ICC 1:100-500
- 
                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
- 
                                            浓度
- 1 μg/μL
- 
                                            缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 
                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 
                                            储存条件
- 4 °C,-20 °C
- 
                                            储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 
                                            有效期
- 12 months
 
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    - LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))
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                                            别名
- DNA Ligase IV/LIG4
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                                            背景
- 
                        Synonyms: LIG4S, DNA ligase 4, DNA ligase IV, Polydeoxyribonucleotide synthase [ATP] 4, LIG4 Background: Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends. 
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                                            基因ID
- 3981
- 
                                            UniProt
- P49917
- 
                                            途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
 抗原
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