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RIMS3 抗体 (AA 21-120)

This anti-RIMS3 antibody is a 兔 多克隆 antibody detecting RIMS3 in WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 和 ICC. Suitable for 人.
产品编号 ABIN1386016
发货至: 中国

Quick Overview for RIMS3 抗体 (AA 21-120) (ABIN1386016)

抗原

See all RIMS3 抗体
RIMS3 (Regulating Synaptic Membrane Exocytosis 3 (RIMS3))

适用

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宿主

  • 21

克隆类型

  • 21
多克隆

标记

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This RIMS3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
  • 抗原表位

    • 14
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    AA 21-120

    预测反应

    Human,Mouse,Rat,Dog,Cow,Horse,Chicken,Rabbit,Zebrafish

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human RIMS3

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    RIMS3 (Regulating Synaptic Membrane Exocytosis 3 (RIMS3))

    别名

    RIMS3

    背景

    Synonyms: NIM 3, NIM3, Rab 3 interacting molecule 3, Regulating synaptic membrane exocytosis 3, Regulating synaptic membrane exocytosis protein 3, RIMS 3, RIMS-3, RIM 3, RIM3, RIM3 gamma, RIMS3, RIMS3_HUMAN.

    Background: Rab 3, a neural/neuroendocrine-specific member of the Rab family, is involved in Ca2+-regulated exocytosis and functions in an inhibitory capacity, controlling the recruitment and pooling of secretory vesicles at the plasma membrane. The Rim (Rab 3 interacting molecule) family of proteins (Rim1, Rim2, Rim3 and Rim4) are multidomain adaptors that regulate Rab 3 activity and sub-sequent neurotransmitter release. Rim3, also known as RIMS3 (regulating synaptic membrane exocytosis 3) or NIM3, is a 308 amino acid member of the Rim family. Localized to the synapse and to cell junctions, Rim3 contains one C2 domain and is thought to play an important role in the regulation of synaptic membrane exocytosis. Rim3, a protein that may be phosphorylated upon DNA damage, is expressed throughout the body with highest levels present in brain tissue.

    基因ID

    9783

    途径

    Stem Cell Maintenance, Synaptic Vesicle Exocytosis
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