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NPC2 抗体 (AA 20-80)

The 兔 多克隆 anti-NPC2 antibody (ABIN1385817) specifically detects NPC2 in WB 和 ELISA. The antibody is reactive with 小鼠 samples.
产品编号 ABIN1385817
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for NPC2 抗体 (AA 20-80) (ABIN1385817)

抗原

See all NPC2 抗体
NPC2 (Niemann-Pick Disease, Type C2 (NPC2))

适用

  • 45
  • 27
  • 15
  • 5
小鼠

宿主

  • 46
  • 5
  • 2

克隆类型

  • 48
  • 5
多克隆

标记

  • 25
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NPC2 antibody is un-conjugated

应用范围

  • 35
  • 18
  • 11
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 8
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-80

    交叉反应

    小鼠

    预测反应

    Human,Rat,Cow,Sheep

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Niemann Pick C2

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    NPC2 (Niemann-Pick Disease, Type C2 (NPC2))

    别名

    NPC2/Niemann Pick C2

    背景

    Synonyms: EDDM1, Epididymal protein 1, Epididymal secretory protein, Epididymal secretory protein E1, HE1, Human epididymis-specic protein 1, Niemann-Pick disease type C2, Niemann-Pick disease type C2 protein, NPC2, NPC2_HUMAN, Tissue specic secretory protein.

    Background: NPC2 is a secreted protein mapping against gene 14q24.3 (1,2). NPC2 regulates the lipid composition of sperm membranes during maturation in the epididymis(1,2). Mutations in the NPC2 gene may cause Nieman-Pick type C2 disease and frontal lobe atrophy (1,2,3). Nieman-Pick type C2 is a fatal hereditary disease characterized by defective lysosome release of cholesterol (3). The disease is caused by HE1 deficiency, a lysosmal protein proven to be undetectable in fibroblasts from NPC2 patients (3). This differentiates NPC2 from NPC1, as NPC1 has HE1 protein present (3).

    途径

    SARS-CoV-2 Protein Interactome
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