FIG4 抗体 (AA 1-100)
Quick Overview for FIG4 抗体 (AA 1-100) (ABIN1385590)
抗原
See all FIG4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-100
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Dog,Sheep,Pig,Chicken,Monkey
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human FIG4
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亚型
- IgG
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anti-FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4) (Center) antibody
FIG4 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4) antibodyFIG4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4) (AA 608-907) antibodyFIG4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4) (AA 846-874), (C-Term) antibodyFIG4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB24204 unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- FIG4 (FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4))
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别名
- FIG4/SAC3
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背景
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Synonyms: 5-bisphosphate 5-phosphatase, Fig4, FIG4_HUMAN, KIAA0274, ALS11, Phosphatidylinositol 3, hSac3, Phosphatidylinositol 3,5 bisphosphate 5 phosphatase, Polyphosphoinositide phosphatase, SAC domain containing protein 3, SAC domain-containing protein 3, SAC3.
Background: FIG4 is a 907 amino acid protein that contains one SAC domain through which it is thought to function as a phosphoinositide phosphatase that may play an important role in signal transduction and vesicle trafficking. Defects in the gene encoding FIG4 are the cause of Charcot-Marie-Tooth disease type 4J (CMT4J) and amyotrophic lateral sclerosis type 11 (ALS11), both of which negatively affect the nervous system. CMT4J is a recessive demyelinating disorder of the peripheral nervous system and is characterized by reduced motor nerve conduction velocities and axonal degeneration. Unlike CMT4J, ALS11 is characterized by the degeneration of upper motor neurons in the brain and lower neurons in the spinal cord, causing paralysis and, ultimately, death.
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途径
- Inositol Metabolic Process
抗原
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