-
- 抗原 See all FIG4 抗体
- FIG4 (FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4))
-
抗原表位
- Center
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This FIG4 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 交叉反应
- Chimpanzee
- 交叉反应 （详细）
- Chimpanzee (100 %)
- 产品特性
-
Rabbit Polyclonal antibody to FIG4 (FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae))
FIG4 antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human FIG4. The exact sequence is proprietary.
- 亚型
- IgG
-
anti-FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4) (AA 341-390) antibody
FIG4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4) (AA 608-907) antibodyFIG4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4) (AA 846-874), (C-Term) antibodyFIG4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB24204 unconjugated
-
- 应用备注
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
- 说明
-
Positive Control: HeLa , HCT116
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
- 抗原
- FIG4 (FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4))
- 别名
- FIG4 (FIG4 产品)
- 别名
- A530089I17Rik antibody, AI326867 antibody, Sac3 antibody, ALS11 antibody, CMT4J antibody, KIAA0274 antibody, SAC3 antibody, YVS antibody, dJ249I4.1 antibody, Kiaa0274 antibody, RGD1311375 antibody, FIG4 phosphoinositide 5-phosphatase antibody, Fig4 antibody, FIG4 antibody
- 背景
-
The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J.
Cellular Localization: Endosome membrane - 分子量
- 104 kDa
- 基因ID
- 9896
- 途径
- Inositol Metabolic Process
-
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