Nitrotyrosine 抗体
Quick Overview for Nitrotyrosine 抗体 (ABIN1385080)
抗原
See all Nitrotyrosine 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
 - 人, 小鼠, 大鼠
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交叉反应 (详细)
 - Nitrotyrosine
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纯化方法
 - Purified by Protein A.
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免疫原
 - KLH conjugated to Nitrotyrosine
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亚型
 - IgG
 
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应用备注
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                        WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 
                                            
限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 1 μg/μL
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缓冲液
 - 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
 - ProClin
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注意事项
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
 - 12 months
 
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                                            : "Hepatic hypoxia-inducible factors inhibit PPARα expression to exacerbate acetaminophen induced oxidative stress and hepatotoxicity."    in: Free radical biology & medicine, Vol. 110, pp. 102-116, (2017)         (PubMed).        
: "Hydrogen-rich water protects against acetaminophen-induced hepatotoxicity in mice." in: World journal of gastroenterology : WJG, Vol. 21, Issue 14, pp. 4195-209, (2015) (PubMed).
: "Down-regulation of superoxide dismutase 1 by PMA is involved in cell fate determination and mediated via protein kinase D2 in myeloid leukemia cells." in: Biochimica et biophysica acta, Vol. 1853, Issue 10 Pt A, pp. 2662-75, (2015) (PubMed).
: "Tert-butylhydroquinone ameliorates doxorubicin-induced cardiotoxicity by activating Nrf2 and inducing the expression of its target genes." in: American journal of translational research, Vol. 7, Issue 10, pp. 1724-35, (2015) (PubMed).
: "NOX4 NADPH Oxidase-Dependent Mitochondrial Oxidative Stress in Aging-Associated Cardiovascular Disease." in: Antioxidants & redox signaling, (2015) (PubMed).
 
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                                            : "Hepatic hypoxia-inducible factors inhibit PPARα expression to exacerbate acetaminophen induced oxidative stress and hepatotoxicity."    in: Free radical biology & medicine, Vol. 110, pp. 102-116, (2017)         (PubMed).        
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- Nitrotyrosine
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物质类
 - Chemical
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背景
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Synonyms: NULL
Background: Nitrotyrosine is a marker for inflammation and nitric oxide (NO) production and is formed in the presence of the active metabolite NO. Because nitrotyrosine is a stable product of multiple pathways, such as the formation of peroxynitrite, its plasma concentration may be a useful determinant of NO-dependent damage in vivo. Nitrotyrosine has been detected in inflammatory processes such as septic shock, rheumatoid arthritis, celiac disease, atherosclerotic plaques and chronic renal failure.
 
抗原
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