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Nitrotyrosine 抗体

Cited in 5+ publications. This 兔 多克隆 anti-Nitrotyrosine antibody specifically detects Nitrotyrosine in WB, ELISA, FACS, IHC (fro), IHC (p), IF (cc) 和 IF (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1385080
发货至: 中国
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中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Nitrotyrosine 抗体 (ABIN1385080)

抗原

See all Nitrotyrosine 抗体
Nitrotyrosine

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Nitrotyrosine antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 交叉反应

    人, 小鼠, 大鼠

    交叉反应 (详细)

    Nitrotyrosine

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated to Nitrotyrosine

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Li, Du, Yuan, Han, Dong, Chen, Wu, Zhang, Xu, Han, Zhang, Xia: "Hepatic hypoxia-inducible factors inhibit PPARα expression to exacerbate acetaminophen induced oxidative stress and hepatotoxicity." in: Free radical biology & medicine, Vol. 110, pp. 102-116, (2017) (PubMed).

    Zhang, Song, Pang, Zhang, Wan, Yuan, Wu, Liu: "Hydrogen-rich water protects against acetaminophen-induced hepatotoxicity in mice." in: World journal of gastroenterology : WJG, Vol. 21, Issue 14, pp. 4195-209, (2015) (PubMed).

    Chen, Kan: "Down-regulation of superoxide dismutase 1 by PMA is involved in cell fate determination and mediated via protein kinase D2 in myeloid leukemia cells." in: Biochimica et biophysica acta, Vol. 1853, Issue 10 Pt A, pp. 2662-75, (2015) (PubMed).

    Wang, Su, Wang, Zhang, Zhang, Niu, Guo, Li, Jiang, Liu, Guo: "Tert-butylhydroquinone ameliorates doxorubicin-induced cardiotoxicity by activating Nrf2 and inducing the expression of its target genes." in: American journal of translational research, Vol. 7, Issue 10, pp. 1724-35, (2015) (PubMed).

    Vendrov, Vendrov, Smith, Yuan, Sumida, Robidoux, Runge, Madamanchi: "NOX4 NADPH Oxidase-Dependent Mitochondrial Oxidative Stress in Aging-Associated Cardiovascular Disease." in: Antioxidants & redox signaling, (2015) (PubMed).

  • 抗原

    Nitrotyrosine

    物质类

    Chemical

    背景

    Synonyms: NULL

    Background: Nitrotyrosine is a marker for inflammation and nitric oxide (NO) production and is formed in the presence of the active metabolite NO. Because nitrotyrosine is a stable product of multiple pathways, such as the formation of peroxynitrite, its plasma concentration may be a useful determinant of NO-dependent damage in vivo. Nitrotyrosine has been detected in inflammatory processes such as septic shock, rheumatoid arthritis, celiac disease, atherosclerotic plaques and chronic renal failure.

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