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IL-10 抗体

This 小鼠 单克隆 antibody specifically detects IL-10 in IHC, ELISA 和 Func. It exhibits reactivity toward 人 和 小鼠. It has been mentioned in 11+ publications
产品编号 ABIN1383949
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IL-10 抗体 (ABIN1383949)

抗原

See all IL-10 (IL10) 抗体
IL-10 (IL10) (Interleukin 10 (IL10))

适用

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人, 小鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This IL-10 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA, Functional Studies (Func)

克隆位点

B-S10
  • 特异性

    Recognises both natural and recombinant human IL-10

    纯化方法

    Ion exchange chromatography

    过滤

    0.22 μm filtered

    免疫原

    Recombinant human IL-10,Myeloma X63/AG.8653 x Balb/c spleen cells

    亚型

    IgG1 kappa

    Biological Activity Comment

    Blocks IL-10 induced inhibition of IL-6 synthesis on LPS activated monocytes
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

    储存液

    Without preservative

    储存条件

    4 °C

    储存方法

    Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
  • Naji, Le Rond, Durrbach, Krawice-Radanne, Creput, Daouya, Caumartin, LeMaoult, Carosella, Rouas-Freiss: "CD3+CD4low and CD3+CD8low are induced by HLA-G: novel human peripheral blood suppressor T-cell subsets involved in transplant acceptance." in: Blood, Vol. 110, Issue 12, pp. 3936-48, (2007) (PubMed).

    Ravirajan, Wang, Matis, Papadaki, Griffiths, Latchman, Isenberg: "Effect of neutralizing antibodies to IL-10 and C5 on the renal damage caused by a pathogenic human anti-dsDNA antibody." in: Rheumatology (Oxford, England), Vol. 43, Issue 4, pp. 442-7, (2004) (PubMed).

    Fontana, Moratto, Mangal, De Francesco, Vermi, Ferrari, Facchetti, Kutukculer, Fiorini, Duse, Das, Notarangelo, Plebani, Badolato: "Functional defects of dendritic cells in patients with CD40 deficiency." in: Blood, Vol. 102, Issue 12, pp. 4099-106, (2004) (PubMed).

    Brok, van Meurs, Blezer, Schantz, Peritt, Treacy, Laman, Bauer, t Hart: "Prevention of experimental autoimmune encephalomyelitis in common marmosets using an anti-IL-12p40 monoclonal antibody." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 11, pp. 6554-63, (2002) (PubMed).

    Debili, Robin, Schiavon, Letestu, Pflumio, Mitjavila-Garcia, Coulombel, Vainchenker: "Different expression of CD41 on human lymphoid and myeloid progenitors from adults and neonates." in: Blood, Vol. 97, Issue 7, pp. 2023-30, (2001) (PubMed).

    Schrijver, van Meurs, Melief, Wim Ang, Buljevac, Ravid, Hazenberg, Laman: "Bacterial peptidoglycan and immune reactivity in the central nervous system in multiple sclerosis." in: Brain : a journal of neurology, Vol. 124, Issue Pt 8, pp. 1544-54, (2001) (PubMed).

    Egeler, Favara, van Meurs, Laman, Claassen: "Differential In situ cytokine profiles of Langerhans-like cells and T cells in Langerhans cell histiocytosis: abundant expression of cytokines relevant to disease and treatment." in: Blood, Vol. 94, Issue 12, pp. 4195-201, (2000) (PubMed).

    Villoslada, Hauser, Bartke, Unger, Heald, Rosenberg, Cheung, Mobley, Fisher, Genain: "Human nerve growth factor protects common marmosets against autoimmune encephalomyelitis by switching the balance of T helper cell type 1 and 2 cytokines within the central nervous system." in: The Journal of experimental medicine, Vol. 191, Issue 10, pp. 1799-806, (2000) (PubMed).

    Balashov, Comabella, Ohashi, Khoury, Weiner: "Defective regulation of IFNgamma and IL-12 by endogenous IL-10 in progressive MS." in: Neurology, Vol. 55, Issue 2, pp. 192-8, (2000) (PubMed).

    Lelievre, Sarrouilhe, Morel, PreudHomme, Wijdenes, Lecron: "Preincubation of human resting T cell clones with interleukin 10 strongly enhances their ability to produce cytokines after stimulation." in: Cytokine, Vol. 10, Issue 11, pp. 831-40, (1999) (PubMed).

    Schandené, Alonso-Vega, Willems, Gérard, Delvaux, Velu, Devos, de Boer, Goldman: "B7/CD28-dependent IL-5 production by human resting T cells is inhibited by IL-10." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 152, Issue 9, pp. 4368-74, (1994) (PubMed).

  • 抗原

    IL-10 (IL10) (Interleukin 10 (IL10))

    别名

    IL-10

    途径

    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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