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CD28 抗体

This anti-CD28 antibody is a 小鼠 单克隆 antibody detecting CD28 in FACS, Func 和 IHC. Suitable for 人. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN1383845
发货至: 中国

Quick Overview for CD28 抗体 (ABIN1383845)

抗原

See all CD28 抗体
CD28

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD28 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Functional Studies (Func), Immunohistochemistry (IHC)

克隆位点

B-T3
  • 特异性

    Recognises the B7/BB1 receptor (B7/BB1 R), a 44 kDa protein

    纯化方法

    Ion exchange chromatography

    过滤

    0.22 μm filtered

    免疫原

    U266 cell line,Myeloma X63/AG.8653 x Balb/c spleen cells

    亚型

    IgG2a, kappa

    Biological Activity Comment

    Inhibits mixed lymphocyte culture. Co-stimulates T-cell proliferation
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

    储存液

    Without preservative

    储存条件

    4 °C

    储存方法

    Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
  • Vermot-Desroches, Sergent, Bonnin, Wijdenes: "Characterization of monoclonal antibodies directed against trail or trail receptors." in: Cellular immunology, Vol. 236, Issue 1-2, pp. 86-91, (2005) (PubMed).

    Roth, Yssel, Pene, Chavez, Schertzer, Lansdorp, Spits, Luiten: "Telomerase levels control the lifespan of human T lymphocytes." in: Blood, Vol. 102, Issue 3, pp. 849-57, (2003) (PubMed).

    Luiten, Péne, Yssel, Spits: "Ectopic hTERT expression extends the life span of human CD4+ helper and regulatory T-cell clones and confers resistance to oxidative stress-induced apoptosis." in: Blood, Vol. 101, Issue 11, pp. 4512-9, (2003) (PubMed).

    Sauce, Bodinier, Garin, Petracca, Tonnelier, Duperrier, Melo, Apperley, Ferrand, Hervé, Lang, Tiberghien, Robinet: "Retrovirus-mediated gene transfer in primary T lymphocytes impairs their anti-Epstein-Barr virus potential through both culture-dependent and selection process-dependent mechanisms." in: Blood, Vol. 99, Issue 4, pp. 1165-73, (2002) (PubMed).

    Jourdan, Abbal, Noraz, Hori, Uchiyama, Vendrell, Bousquet, Taylor, Pène, Yssel, Nora: "IL-4 induces functional cell-surface expression of CXCR4 on human T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 160, Issue 9, pp. 4153-7, (1998) (PubMed).

  • 抗原

    CD28

    别名

    CD28

    分子量

    44 kDa

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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