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PKM2 抗体 (pSer37)

This anti-PKM2 antibody is a 兔多克隆 antibody detecting PKM2 in WB. Suitable for 人. This Primary Antibody has been cited in 1 publication.

(1 reference)

产品编号 ABIN1355883

发货至: 中国

Quick Overview for PKM2 抗体 (pSer37) (ABIN1355883)

抗原

See all PKM2 抗体

PKM2 (Pyruvate Kinase M2 (PKM2))

适用

115
65
55
4
4
2
2
2
2
2
1
1
1
1
1

人

宿主

兔

克隆类型

多克隆

标记

77
5
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1

This PKM2 antibody is un-conjugated

应用范围

98
33
30
30
27
27
24
22
17
15
7
5
2
2
2
1
1
1
1

Western Blotting (WB)

Discover our top product PKM2 Primary Antibody

抗原表位
21

16

8

8

7

7

6

4

4

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer37

特异性

The antibody detects endogenous level of PKM2 only

免疫原

Peptide sequence around phosphorylation site of pSer37 (I-D-S (p) -P-P) derived from Human PKM2.
anti-Pyruvate Kinase M2 (PKM2) (AA 294-470) antibody
PKM2 适用: 人 WB, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 141-248) antibody
PKM2 适用: 人 WB, IHC, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (pTyr105) antibody
PKM2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 476-505), (C-Term) antibody
PKM2 适用: 人, 小鼠, 大鼠, 猴 WB, IHC (p), IF 宿主: 兔 Polyclonal RB3697 unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 383-417), (C-Term) antibody
PKM2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18405 unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 116-145) antibody
PKM2 适用: 人 WB, IHC, FACS, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 476-505) antibody
PKM2 适用: 人, 小鼠, 大鼠, 灵长类 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 255-350) antibody
PKM2 适用: 人, 小鼠, 大鼠 WB, FACS, ELISA, IHC (p), ICC, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 1-531) antibody
PKM2 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 51-150) antibody
PKM2 适用: 人, 小鼠, 大鼠 WB, FACS, ELISA, IHC (p), ICC, IF (p), IF (cc), IHC (fro) 宿主: 小鼠 Polyclonal unconjugated

应用备注

Western Blot: 1:500-1000

限制

仅限研究用
状态

Liquid

储存条件

4 °C/-20 °C
Yang, Zheng, Xia, Ji, Chen, Guo, Lyssiotis, Aldape, Cantley, Lu: "ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect." in: Nature cell biology, Vol. 14, Issue 12, pp. 1295-304, (2012) (PubMed).
抗原

PKM2 (Pyruvate Kinase M2 (PKM2))

别名

PKM2

背景

Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.

分子量

60 kDa

途径

Warburg Effect

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