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MCAM 抗体

This anti-MCAM antibody is a 小鼠 单克隆 antibody detecting MCAM in FACS. Suitable for 小鸡.
产品编号 ABIN135586
发货至: 中国

Quick Overview for MCAM 抗体 (ABIN135586)

抗原

See all MCAM 抗体
MCAM (Melanoma Cell Adhesion Molecule (MCAM))

适用

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小鸡

宿主

  • 108
  • 101
  • 2
  • 1
  • 1
  • 1
小鼠

克隆类型

  • 115
  • 99
单克隆

标记

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  • 1
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  • 1
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This MCAM antibody is un-conjugated

应用范围

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  • 5
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Flow Cytometry (FACS)

克隆位点

C264
  • 特异性

    Chicken/Turkey MCAM, Mr 98 kDa

    产品特性

    Mouse Anti-Chicken MCAM-UNLB

    纯化方法

    Purified

    免疫原

    Mixture of E15 and E16 thymocytes from H.B15, H.B19, and H.B21 chicken embryos

    亚型

    IgG2b
  • 应用备注

    • Applications: FC - Quality tested , ICC - Reported in literature , IP - Reported in literature
    • Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and BIOT conjugates 1 g/106 cells PE conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

    样本量

    1 mL

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

    储存液

    Without preservative

    注意事项

    Each reagent is stable for the period shown on the bottle label if stored as directed.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C
  • 抗原

    MCAM (Melanoma Cell Adhesion Molecule (MCAM))

    别名

    MCAM

    背景

    Chicken MCAM, a member of the immunoglobulin superfamily of cell surface receptors, consists of the V-V-C2-C2-C2 Ig domains. It is a single chain glycoprotein with three mRNA splice variants. One has a short cytoplasmic tail, another has a long tail, and the third seems to lack transmembrane and cytoplasmic regions. It is highly homologous to gicerin, a molecule involved in neurite outgrowth and Wilm's kidney tumor progression in the chicken, and to the human melanoma progression molecule MUC18. Chicken MCAM is expressed by c-kit+ hematopoietic progenitor cells in embryonic bone marrow, thymocytes, and capillary endothelial cells. MCAM-expressing cells sorted from bone marrow are enriched in progenitors capable of differentiating into T cells when transferred into the appropriate thymic microenvironment. MCAM has been proposed to be involved in cellular adhesion and homing processes.
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