FOXA2 抗体 (AA 435-439)
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Quick Overview for FOXA2 抗体 (AA 435-439) (ABIN1355837)
抗原
See all FOXA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 435-439
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特异性
- The antibody detects endogenous level of total FoxA2 (HNF3b) protein.
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免疫原
- Peptide sequence around AA 435-439 ( A-S-P-L-A) derived from Human FoxA2 (HNF3b) . Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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anti-Forkhead Box A2 (FOXA2) (AA 363-457) antibody
FOXA2 适用: 人 WB, ELISA, IF, IP, RNAi 宿主: 小鼠 Monoclonal 7E6 unconjugated
anti-Forkhead Box A2 (FOXA2) (Middle Region) antibodyFOXA2 适用: 人, 小鼠, 大鼠, 犬, 兔, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box A2 (FOXA2) (C-Term) antibodyVerified FOXA2 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Forkhead Box A2 (FOXA2) (AA 201-300) antibodyFOXA2 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box A2 (FOXA2) (AA 363-457) antibodyFOXA2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4G11 unconjugated
anti-Forkhead Box A2 (FOXA2) (AA 363-457) antibodyFOXA2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F12 unconjugated
anti-Forkhead Box A2 (FOXA2) (AA 380-407) antibodyFOXA2 适用: 人, 大鼠 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box A2 (FOXA2) (AA 128-157) antibodyFOXA2 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box A2 (FOXA2) antibodyFOXA2 适用: 人 WB, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Forkhead Box A2 (FOXA2) antibodyFOXA2 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 7H4B7 unconjugated
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应用备注
- Western blotting: 1:500-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- FOXA2 (Forkhead Box A2 (FOXA2))
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别名
- FoxA2(HNF3beta)
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背景
- Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' . In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs, FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally discribed as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis, regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
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分子量
- 50 kDa
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NCBI登录号
- NP_068556
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UniProt
- Q9Y261
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途径
- Dopaminergic Neurogenesis, Regulation of Carbohydrate Metabolic Process
抗原
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