H-2Kd/H-2Dd 抗体 (Biotin)
Quick Overview for H-2Kd/H-2Dd 抗体 (Biotin) (ABIN135418)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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                                            特异性
- Mouse H-2Kd/H-2Dd
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                                            产品特性
- Mouse Anti-Mouse H-2Kd/H-2Dd-BIOT
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                                            免疫原
- BDF1 mouse splenocytes
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                                            亚型
- IgG2a
 
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                                            应用备注
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                        - Applications: FC - Quality tested , ICC - Reported in literature , EM - Reported in literature , IP - Reported in literature , CMCD - Reported in literature , Block - Reported in literature , Adhesion - Reported in literature
- Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and BIOT conjugates 1 g/106 cells PE conjugate 0.1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
 
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                                            说明
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                        Blocking Cell Adhesion, Complement-mediated cytotoxicity 
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                                            样本量
- 1 mL
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                                            限制
- 仅限研究用
 
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                                            浓度
- 0.5 mg/mL
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                                            缓冲液
- 0.5 mg in 1.0 mL of PBS/Sodium azide
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            注意事项
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                         Protect conjugated products from light. 
 Each reagent is stable for the period shown on the bottle label if stored as directed.
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                                            储存条件
- 4 °C
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                                            储存方法
- Store at 2-8°C
 
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    - 
                                            : "HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties."    in: eLife, Vol. 7, (2019)         (PubMed).        
 : "Usp9x Promotes Survival in Human Pancreatic Cancer and Its Inhibition Suppresses Pancreatic Ductal Adenocarcinoma In Vivo Tumor Growth." in: Neoplasia (New York, N.Y.), Vol. 20, Issue 2, pp. 152-164, (2018) (PubMed).
 : "Inhibition of PI3K/Akt/mTOR signaling in PI3KR2-overexpressing colon cancer stem cells reduces tumor growth due to apoptosis." in: Oncotarget, Vol. 8, Issue 31, pp. 50476-50488, (2017) (PubMed).
 
 
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                                            : "HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties."    in: eLife, Vol. 7, (2019)         (PubMed).        
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    - H-2Kd/H-2Dd
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                                            背景
- The classical MHC Class I molecules are histocompatibility antigens encoded by the H-2 gene complex and consist of heterodimers of highly polymorphic chains noncovalently associated with the invariant 2-microglobulin. These antigens are expressed on most nucleated cells but expression varies on different cell types. MHC Class I molecules present endogenously synthesized peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. MHC Class I antigens expressed on thymic epithelial cells regulate the positive and negative selection of CD8+ T cells during T cell ontogeny.
 抗原
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