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H-2Kd/H-2Dd 抗体

适用: 小鼠 FACS 宿主: 小鼠 Monoclonal 34-1-2S unconjugated
产品编号 ABIN135416
发货至: 中国
  • 抗原
    H-2Kd/H-2Dd
    适用
    小鼠
    宿主
    • 7
    小鼠
    克隆类型
    • 7
    单克隆
    标记
    • 2
    • 2
    • 2
    • 1
    非结合性
    应用范围
    • 7
    • 3
    • 2
    • 1
    Flow Cytometry (FACS)
    特异性
    Mouse H-2Kd/H-2Dd
    产品特性
    Mouse Anti-Mouse H-2Kd/H-2Dd-UNLB
    纯化方法
    Purified
    免疫原
    BDF1 mouse splenocytes
    克隆位点
    34-1-2S
    亚型
    IgG2a
  • 应用备注
    • Applications: FC - Quality tested , ICC - Reported in literature , EM - Reported in literature , IP - Reported in literature , CMCD - Reported in literature , Block - Reported in literature , Adhesion - Reported in literature
    • Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and BIOT conjugates 1 g/106 cells PE conjugate 0.1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    说明

    Blocking Cell Adhesion, Complement-mediated cytotoxicity

    样本量
    1 mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added
    储存液
    Without preservative
    注意事项
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C
  • 抗原
    H-2Kd/H-2Dd
    背景
    The classical MHC Class I molecules are histocompatibility antigens encoded by the H-2 gene complex and consist of heterodimers of highly polymorphic chains noncovalently associated with the invariant 2-microglobulin. These antigens are expressed on most nucleated cells but expression varies on different cell types. MHC Class I molecules present endogenously synthesized peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. MHC Class I antigens expressed on thymic epithelial cells regulate the positive and negative selection of CD8+ T cells during T cell ontogeny.
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