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H-2Kd/H-2Dd 抗体

This anti- antibody is a 小鼠 单克隆 antibody detecting in FACS. Suitable for 小鼠.
产品编号 ABIN135416
发货至: 中国

Quick Overview for H-2Kd/H-2Dd 抗体 (ABIN135416)

抗原

H-2Kd/H-2Dd

适用

小鼠

宿主

  • 7
小鼠

克隆类型

  • 7
单克隆

标记

  • 2
  • 2
  • 2
  • 1
非结合性

应用范围

  • 7
  • 3
  • 2
  • 1
Flow Cytometry (FACS)

克隆位点

34-1-2S
  • 特异性

    Mouse H-2Kd/H-2Dd

    产品特性

    Mouse Anti-Mouse H-2Kd/H-2Dd-UNLB

    纯化方法

    Purified

    免疫原

    BDF1 mouse splenocytes

    亚型

    IgG2a
  • 应用备注

    • Applications: FC - Quality tested , ICC - Reported in literature , EM - Reported in literature , IP - Reported in literature , CMCD - Reported in literature , Block - Reported in literature , Adhesion - Reported in literature
    • Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and BIOT conjugates 1 g/106 cells PE conjugate 0.1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

    说明

    Blocking Cell Adhesion, Complement-mediated cytotoxicity

    样本量

    1 mL

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

    储存液

    Without preservative

    注意事项

    Each reagent is stable for the period shown on the bottle label if stored as directed.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C
  • 抗原

    H-2Kd/H-2Dd

    背景

    The classical MHC Class I molecules are histocompatibility antigens encoded by the H-2 gene complex and consist of heterodimers of highly polymorphic chains noncovalently associated with the invariant 2-microglobulin. These antigens are expressed on most nucleated cells but expression varies on different cell types. MHC Class I molecules present endogenously synthesized peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. MHC Class I antigens expressed on thymic epithelial cells regulate the positive and negative selection of CD8+ T cells during T cell ontogeny.
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