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- 抗原 See all IL2 Receptor beta (IL2RB) 抗体
- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This IL2 Receptor beta antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 特异性
- Mouse CD122, 90-100 kDa
- 交叉反应 （详细）
- Cross-reactivity with Stat1 from other sources has not been determined.
- 预测反应
- A BLAST analysis was used to suggest cross-reactivity with Stat1 from mouse and rat based on 100% homology with the immunizing sequence. Partial reactivity is expected against Stat1 from human sources as 90% homology is noted.
- 产品特性
- Rat Anti-Mouse CD122-UNLB
- 纯化方法
- Purified
- 免疫原
- Rat myeloma YB2/0 transfected with truncated IL-2Rbeta cDNA (YB2/0-mbetat-28)
- 克隆位点
- 5H4
- 亚型
- IgG2a
- Top Product
- Discover our top product IL2RB Primary Antibody
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anti-Interleukin 2 Receptor, beta (IL2RB) (AA 27-240) antibody
IL2RB 适用: 人 WB, FACS, ELISA, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 1G11C6 unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) (Internal Region) antibodyIL2RB 适用: 小鼠, 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) antibodyIL2RB 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) antibodyIL2RB 适用: 人 FACS, IP, Func 宿主: 小鼠 Monoclonal TU27 unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) antibodyIL2RB 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal TU27 unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) antibody (APC)IL2RB 适用: 人 FACS 宿主: 小鼠 Monoclonal TU27 APC
anti-Interleukin 2 Receptor, beta (IL2RB) (Tyr364) antibodyIL2RB 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) (AA 1-551) antibodyIL2RB 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) (AA 1-551) antibodyIL2RB 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) (N-Term) antibodyIL2RB 适用: 小鼠, 人 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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- Applications: FC - Quality tested , IP - Reported in literature
- Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE and APC conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- 样本量
- 1 mL
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added
- 储存液
- Without preservative
- 注意事项
- Each reagent is stable for the period shown on the bottle label if stored as directed.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C
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- 抗原
- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
- 别名
- CD122 (IL2RB 产品)
- 别名
- IL2RB antibody, il-2rb antibody, CD122 antibody, IL15RB antibody, P70-75 antibody, IL2RBC antibody, IL-15Rbeta antibody, IL15Rbeta antibody, Il-2/15Rbeta antibody, Il-2Rbeta antibody, p70 antibody, interleukin 2 receptor subunit beta antibody, interleukin-2 receptor subunit beta antibody, interleukin 2 receptor, beta antibody, interleukin 2 receptor, beta chain antibody, IL2RB antibody, LOC510185 antibody, il2rb antibody, Il2rb antibody
- 背景
- The IL-2 receptor is a complex of three distinct polypeptide chains: (i) the chain which binds IL-2 with low affinity, (ii) the chain that binds IL-2 with high affinity, and (ii) the common chain (C) that does not bind IL-2. The high affinity receptor complex is an α/β/γ heterotrimer with a kDa of 1.3 x 10-11 M.2 In mouse spleen, CD122 is expresed on 30 % of CD8+ cells and all NK cells, but < 1 % of B cells and CD4+ T lymphocytes. In the thymus, its expression is confined to CD4-CD8+ single positive and CD4-CD8- double negative cells. Cytoplasmic regions of the IL-2R chain are involved in IL-2-mediated cellular signaling and, via the interaction of IL-2 and its receptor complex, may be involved in the generation and differentiation of T lymphocytes.
- 途径
- JAK/STAT Signaling, Growth Factor Binding
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