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CD24 抗体

This anti-CD24 antibody is a 大鼠 单克隆 antibody detecting CD24 in FACS. Suitable for 小鼠.
产品编号 ABIN135358
发货至: 中国

Quick Overview for CD24 抗体 (ABIN135358)

抗原

See all CD24 抗体
CD24 (CD24 Molecule (CD24))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD24 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

30-F1
  • 特异性

    Mouse CD24, Mr 35-45 kDa

    产品特性

    Rat Anti-Mouse CD24-UNLB

    纯化方法

    Purified

    免疫原

    Mouse thymus or spleen

    亚型

    IgG2c
  • 应用备注

    • Applications: FC - Quality tested
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 2 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

    样本量

    1 mL

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

    储存液

    Without preservative

    注意事项

    Each reagent is stable for the period shown on the bottle label if stored as directed.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C
  • 抗原

    CD24 (CD24 Molecule (CD24))

    别名

    CD24

    背景

    CD24 is expressed in B cells until their terminal differentiation into plasma cells. It has been used widely as a marker to fractionate different B-lineage differentiation stages. CD24 has been found on a variety of other hematopoietic and neural cell types, and is now classified as a costimulatory molecule. The CD24/HSA molecule is composed mostly of carbohydrate, with a protein core of only 31-35 amino acids in the human and 27 AA in the mouse. The molecular mass is variable, ranging from 38-70 kDa. CD24 is now included in the large group of phosphatidylinositol-anchored membrane proteins. Studies with purified CD24 applied to latex beads have demonstrated a self-binding property, suggesting that the molecule is capable of promoting homotypic aggregation, binding and cell adhesion. This is supported by earlier observations of the blockade of B cell lymphoblast aggregation with anti-CD24 monoclonal antibody. Recent studies of murine CD24 have assigned a role for CD24/HSA as a ligand for P-selectin, a calcium-dependent lectin.

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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