CTLA4 抗体
Quick Overview for CTLA4 抗体 (ABIN135317)
抗原
See all CTLA4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Mouse CD152, Mr 33-37 kDa
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产品特性
- Hamster Anti-Mouse CD152-LE/AF
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内毒素水平
- Low endotoxin
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免疫原
- Extracellular portion of murine CTLA-4 fused to a murine IgG2a
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亚型
- IgG
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应用备注
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- Applications: ELISA - Quality tested , FLISA - Quality tested FC - Reported literature , Stim - Reported in literature
- Working Dilutions: ELISA BIOT conjugate 1:5,000 - 1:10,000 FLISA FITC conjugate 1:100 - 1:400 PE conjugate 1 g/mL Flow Cytometry FITC and BIOT conjugates 3 g/106 cells PE conjugate 0.3 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
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说明
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In vitro functional studies
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样本量
- 1 mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- 0.5 mg of purified immunoglobulin in 1.0 mL of PBS
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储存液
- Azide free
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注意事项
- Each reagent is stable for the period shown on the bottle label if stored as directed.
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储存条件
- -20 °C
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储存方法
- Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
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- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
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别名
- CD152
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背景
- The lymphocyte surface antigen CD152, also known as CTLA-4, is related to the co-stimulatory molecule CD28, and both molecules share common B7 family counter-receptors. However CD152 is thought to be a negative regulator of T cell activation and may play a role in apoptotic control of T cells. CD152 exists as a 69 kDa homodimer, and is relatively conserved among humans, mice and chickens.
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途径
- Cancer Immune Checkpoints
抗原
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