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CD80 抗体

The 大鼠 单克隆 anti-CD80 antibody is suitable to detect CD80 in samples from 小鼠. It has been validated for FACS, IP 和 BR.
产品编号 ABIN135272
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD80 抗体 (ABIN135272)

抗原

See all CD80 抗体
CD80

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD80 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Blocking Reagent (BR)

克隆位点

1G10
  • 原理

    Rat Anti-Mouse CD80-LE/AF

    特异性

    Mouse CD80, Mr 52-55 kDa

    产品特性

    Low Endotoxin/Azide Free Anti-Mouse CD80 antibody for use in flow cytometry, immunoprecipitation, and blocking assays.

    内毒素水平

    Low Endotoxin

    免疫原

    Activated 5C2 cells

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Phosphate buffered saline, pH 7.4

    储存液

    Azide free

    注意事项

    Each reagent is stable for the period shown on the bottle label if stored as directed.

    储存条件

    4 °C

    储存方法

    2-8°C
  • 抗原

    CD80

    别名

    CD80

    背景

    CD80 (B7-1) is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed by dendritic cells, monocytes, and peritoneal macrophages. Expression of CD80 on B cells is upregulated after activation by various means including stimulation by LPS, IL-4, and surface Ig receptor cross linking with peak expression occurring between 48 and 72 hours post-activation. The interaction of CD80/B7-1 with its ligands, CD28 and CD152/CTLA-4, provides a potent costimulatory signal for T cells activated through the CD3/T cell receptor complex.

    基因ID

    12519

    UniProt

    Q00609

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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