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CD80 抗体 (PE)

This anti-CD80 antibody is a 大鼠 单克隆 antibody detecting CD80 in FACS. Suitable for 小鼠.
产品编号 ABIN135271
发货至: 中国

Quick Overview for CD80 抗体 (PE) (ABIN135271)

抗原

See all CD80 抗体
CD80

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD80 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

1G10
  • 特异性

    Mouse CD80, Mr 52-55 kDa

    产品特性

    Rat Anti-Mouse CD80-PE

    纯化方法

    Ion exchange column

    免疫原

    Activated 5C2 cells

    亚型

    IgG2a
  • 应用备注

    • Applications: FC - Quality tested , IP - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

    说明

    In vivo and in vitro blocking of ligand binding

    样本量

    1 mL

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    0.1 mg in 1.0 mL or 0.2 mg in 2.0 mL of PBS/Sodium azide and a stabilizing agent

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze!
    Protect conjugated products from light.

    Each reagent is stable for the period shown on the bottle label if stored as directed.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C
  • 抗原

    CD80

    别名

    CD80

    背景

    CD80 (B7-1) is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed by dendritic cells, monocytes, and peritoneal macrophages. Expression of CD80 on B cells is upregulated after activation by various means including stimulation by LPS, IL-4, and surface Ig receptor cross linking with peak expression occurring between 48 and 72 hours post-activation. The interaction of CD80/B7-1 with its ligands, CD28 and CD152/CTLA-4, provides a potent costimulatory signal for T cells activated through the CD3/T cell receptor complex.

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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