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ICAM1 抗体

This anti-ICAM1 antibody is a 大鼠 单克隆 antibody detecting ICAM1 in FACS. Suitable for 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN135246
发货至: 中国

Quick Overview for ICAM1 抗体 (ABIN135246)

抗原

See all ICAM1 抗体
ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This ICAM1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

YN1-1-7-4
  • 特异性

    Mouse/Porcine CD54, Mr 95 kDa

    产品特性

    Rat Anti-Mouse CD54-UNLB

    纯化方法

    Purified

    免疫原

    Mouse NS-1 cells

    亚型

    IgG2b
  • 应用备注

    • Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , WB - Reported in literature , IP - Reported in literature , Block - Reported in literature , Purification - Reported in literature
    • Working Dilutions: Flow Cytometry FITC, BIOT, AF488, and PACBLU conjugates 1 g/106 cells PE, APC, AF647, and AF700 conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

    说明

    In vitro blocking studies

    样本量

    1 mL

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

    储存液

    Without preservative

    注意事项

    Each reagent is stable for the period shown on the bottle label if stored as directed.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C
  • Chung, Kim, An, Lee, Lim, Kang, Kwon: "Coxsackievirus and adenovirus receptor mediates the responses of endothelial cells to fluid shear stress." in: Experimental & molecular medicine, Vol. 51, Issue 11, pp. 1-15, (2020) (PubMed).

  • 抗原

    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

    别名

    CD54

    背景

    CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes and lymphocytes. Its expression is upregulated by inflammatory mediators such as IFN-γ, IL-1, TNF-α, lipopolysaccharide and phorbol esters. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels, particularly in areas of inflammation. CD54 on antigen-presenting cells contributes to antigen-specific T-cell activation, presumably by enhancing interactions between T cell and antigen-presenting cells. These adhesion reactions are mediated via the binding of CD54 to its major ligands, LFA-1 and Mac-1.

    途径

    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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