CD38 抗体
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北京 101111
Quick Overview for CD38 抗体 (ABIN135205)
抗原
See all CD38 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Rat Anti-Mouse CD38-LE/AF
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特异性
- Mouse CD38, Mr 42 kDa
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产品特性
- Low Endotoxin/Azide Free Anti-Mouse CD38 antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, ELISA, separation, activation, costimulation, stimulation, apoptosis, drug delivery, and blocking assays.
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内毒素水平
- Low Endotoxin
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免疫原
- BCL1 plasma membrane glycoproteins
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亚型
- IgG2a
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anti-CD38 (AA 1-300) antibody
适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD38 (AA 241-270), (C-Term) antibody适用: 人 FACS, WB, IF, IHC (p) 宿主: 兔 Polyclonal RB18001 unconjugated
anti-CD38 (AA 46-300) antibody适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD38 (AA 43-300) antibody适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 5C5C3 unconjugated
anti-CD38 (C-Term) antibody适用: 人 FACS, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD38 (AA 241-270) antibody适用: 人 FACS, WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CD38 antibody (APC)适用: 人 FACS 宿主: 小鼠 Monoclonal HIT2 APC
anti-CD38 antibody适用: 人 FACS, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal HIT2 unconjugated
anti-CD38 antibody (PE)适用: 人 FACS 宿主: 小鼠 Monoclonal HIT2 PE
anti-CD38 (AA 131-145), (Extracellular) antibody适用: 小鼠 FACS, WB, IHC, LCI 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate buffered saline, pH 7.4
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储存液
- Azide free
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注意事项
- Each reagent is stable for the period shown on the bottle label if stored as directed.
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储存条件
- 4 °C
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储存方法
- 2-8°C
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- CD38
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背景
- Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells, and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCR+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice, but not by unstimulated bone-marrow-derived macrophages. Monoclonal antibodies to CD38 have been shown to induce B- and T-cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis.
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基因ID
- 12494
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UniProt
- P56528
抗原
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